台湾紫杉中新发现的紫杉烷二萜

Ya‐Ching Shen, Yao-To Chang, Shih-Sheng Wang, Yu-Ling Pan, Kuang-Liang Lo, Yu-Chi Lin
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引用次数: 2

摘要

本文介绍了近年来在台湾红豆杉和苏门答腊红豆杉的根、皮、种子、叶和茎中发现的新的具有生物活性的紫杉烷二萜类化合物。包括taxumatrols A和B(36,37)在内的30多个新化合物已被分离出来,并通过光谱分析、化学衍生化和相关分析确定了它们的结构。一些分离的类taxoids对人肿瘤细胞显示出强大的细胞毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel Taxane Diterpenoids from Taiwanese Yew Trees
Recent discovery of new and bioactive taxane diterpenoids from the roots, barks, seeds, leaves and the stems of Taxus mairei and T. sumatrana, Taiwanese yew trees are described. More than thirty new compounds including taxumatrols A and B (36, 37) have been isolated and their structures determined by spectroscopic analysis and chemical derivatization and correlation. Some of the isolated taxoids exhibited potent cytotoxicity against human tumor cells.
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