用计算机方法对Thiruvarur地区具有保肝潜能的传统悉达医生进行定量民族植物学调查

S. Vijayakumar, J.P. Harikrishnan, S. Prabhu, J.E. Morvin Yabesh, P. Manogar
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引用次数: 17

摘要

本研究的目的是记录来自印度泰米尔纳德邦Thiruvarur地区的传统悉达医生的知识,并对数据进行定量分析,以确定一些有用的药用植物线索并筛选植物化合物。在泰米尔纳德邦的Thiruvarur地区进行了为期1年的实地研究。民族医学信息是从悉达医生那里收集的。对收集到的数据进行定量分析。利用薛定谔套件对3种上市药物和11种不同药用植物化合物对HBeAg进行分子对接研究。在Thiruvarur,共有33种植物被传统Siddha从业者鉴定为常用的民族药用植物,分布于22科22属。分子对接研究中一个有趣的点是木犀草素与商业药物相比是一种有效的抑制HBV的抑制剂。传统的悉达医生和非凡的药用植物知识和用途被记录在研究区域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative Ethnobotanical Survey of Traditional Siddha Medical Practitioners from Thiruvarur District with Hepatoprotective Potentials through In Silico Methods

The aim of the present study was to document the knowledge of traditional Siddha medical practitioners from Thiruvarur district in Tamil Nadu, India, and to quantitatively analyze the data to identify some useful leads of medicinal plants and to screening the phytocomounds. Field study was carried out for a period of 1 year in Thiruvarur district of Tamil Nadu. The ethnomedicinal information were collected from Siddha medical practitioners. The collected data were analyzed through quantitative analysis. The molecular docking studies were performed three marketed drugs and eleven different medicinal plant compounds against HBeAg using Schrodinger suite. A total of 33 species of plants distributed in 22 genera belonging to 22 families were identified as commonly used ethno medicinal plants by traditional Siddha practitioners in Thiruvarur. An interesting point in molecular docking study is that luteolin is an effective inhibitor for the inhibition of HBV when compared to commercial drugs. Traditional Siddha medical practitioner and remarkable medicinal plant knowledge and uses were documented for the study area.

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