儿科重症监护病房儿童溺水的结局

IF 0.5 Q4 PEDIATRICS
Rebecca K. Aures, J. Rosenthal, Ashley Chandler, T. Raybould, M. Flaherty
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引用次数: 0

摘要

溺水仍然是儿童死亡的主要原因。对这些溺水幸存但需要重症监护的患者的结局缺乏了解。我们的目的是研究儿科重症监护病房(PICU)溺水患者的当前死亡率,描述干预措施和相关诊断,并检查与死亡风险相关的因素。我们利用2010年1月1日至2019年12月31日期间143个picu的虚拟儿科系统数据库数据进行了一项回顾性多中心队列研究。患者年龄在0 - 18岁之间,被诊断为溺水者被纳入PICU。主要结局为出院前死亡。预测因子包括人口统计学、重症监护干预和相关诊断。比值比采用多元逻辑回归计算。在整个研究期间,有4855名溺水患者入院。该队列的PICU总死亡率为18.7%。与死亡几率增加相关的因素包括从外部医院转运、机械通气、中央静脉置管、心脏骤停、呼吸衰竭和缺氧缺血性脑病。在2479例需要机械通气的患者中,63例接受体外膜氧合治疗,与死亡率无关。这些数据为需要重症监护的儿童溺水受害者及其预后提供了最新的见解,因为这与他们接受的干预措施有关。在重症监护病房溺水的总死亡率高于重症监护病房的总死亡率和其他损伤原因的死亡率。这些发现对ICU环境中溺水儿童的护理和持续的预防工作具有启示意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes of Pediatric Drowning in the Pediatric Intensive Care Unit
Drowning remains a leading cause of death in children. Knowledge of outcomes of these patients who survive drowning but require critical care is lacking. We aim to study the current mortality rate, describe interventions and associated diagnoses, and examine factors related to risk of death in drowning victims admitted to the pediatric intensive care unit (PICU). We conducted a retrospective multicenter cohort study utilizing data from the Virtual Pediatric Systems Database in 143 PICUs between January 1, 2010, and December 31, 2019. Patients between 0 and 18 years of age admitted to a PICU with a diagnosis of drowning were included. The primary outcome was death prior to hospital discharge. Predictors included demographics, critical care interventions, and associated diagnoses. Odds ratios were calculated using multivariate logistic regression. There were 4,855 patients admitted with drowning across the study period. The overall PICU mortality rate in this cohort was 18.7%. Factors associated with an increased odds of death included being transported from an outside hospital, mechanical ventilation, central line placement, cardiac arrest, respiratory failure, and hypoxic ischemic encephalopathy. In 2,479 patients requiring mechanical ventilation, 63 were treated with extracorporeal membrane oxygenation which was not associated with mortality. This data provide updated insight into pediatric drowning victims requiring critical care and their prognosis, as it relates to the interventions they receive. Overall PICU mortality rates for drowning are higher than overall PICU mortality and mortality from other causes of injury. These findings have implications for the care of drowned children in ICU environments and in continued preventive efforts.
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