用计算机技术估计血液微循环状态的诊断视频显微镜

G. B. Nazarenko, T. S. Heilo
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引用次数: 0

摘要

开发了一种诊断和监测血液微循环状态的方法,包括使用专门开发并注册用于临床使用的设备OKO毛细管镜,在人眼球结膜微血管血流大量增加的情况下,使用特殊软件进行无创非接触式视频记录,该软件允许:测量单个小动脉、小静脉和主要首选通道中红细胞的速度;以固定微血管中可能存在的淤血证、瘀血的红细胞运动;评价左右眼毛细血管的数量和形态,有无小静脉吻合,结膜微血管血流的同一性;测量小动脉直径和小静脉。该方法旨在静息结膜微循环参数的临床研究,它允许将微循环系统的血管内(流变学)部分的记录参数外推到整个生物体的微循环动力学状态,这反映了一般的稳态状态。该方法可用于控制和监测任何实验、运动或治疗目的的研究中个人或患者的一般状况,因为确定的微循环数字参数允许评估一个人的一般状况,对身体活动的反应,并预测患者体内任何全身或局部退行性变化的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DIAGNOSTIC VIDEO MICROSCOPE FOR ESTIMATING THE STATE OF MICROCIRCULATION OF THE BLOOD USING COMPUTER TECHNOLOGIES
A method for diagnosing and monitoring the blood microcirculation state has been developed, including the use of the specially developed and registered for clinical use of the device OKO Capillaroscope for non-invasive non-contact video recording under a large increase in blood flow in the microvessels of the bulbar conjunctiva of the human eye using special software that allows: to measure the speed of red blood cells in individual arterioles, venules and in the main preferred channels; to fix in the microvessels the possible presence of sludge syndrome, stasis of the erythrocyte movement; to evaluate the number and shape of capillaries, the presence of arteriolar-venular anastomoses, the identity of blood flow in the microvessels of the conjunctiva in the right and left eyes; measure arteriole diameters and venules. The method is aimed at a clinical study of the parameters of the microcirculation of the conjunctiva at rest, which allows extrapolating the recorded parameters of the intravascular (rheological) part of the microcirculation system to the state of the microhemodynamics of the whole organism, which reflects the state of general homeostasis. The method can be applied to control and monitor the general condition of a person or patient in any research in experimental, sports or therapeutic purposes, since the determined digital parameters of microcirculation allow to assess the general condition of a person, the response to physical activity and predict the development of any general or local degenerative changes in the patient’s body.
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