{"title":"饮食中的植物化学物质和癌症化学预防","authors":"A. Sheikh, A. Arora, N. Chauhan","doi":"10.18231/j.ijpca.2023.020","DOIUrl":null,"url":null,"abstract":"The goal of cancer chemotherapy is to prevent or slow the growth of tumors by using various Biological or natural agents. Epidemiological and pre-clinical data indicate that phytochemicals can influence cell proliferation and cell cycle regulation, are typically involved in multiple signaling pathways that are frequently disrupted during tumour initiation, proliferation, and propagation, strengthen the host immune system, and make cancer cells more susceptible to cell-damaging agents. Only a small subset of these medicines have undergone clinical testing, and the results of those trials have been inconsistent, despite favorable outcomes from Experimental investigation. Recognizing the impact of these dietary changes may inspire easy and affordable solutions to improve health globally as the global rate of cancer continues to rise. In this article, we provide a summary of the information on a few phytochemicals with a particular focus on the clinical data demonstrating these compounds' effectiveness in populations at significant risk.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dietary phytochemicals and cancer chemoprevention\",\"authors\":\"A. Sheikh, A. Arora, N. Chauhan\",\"doi\":\"10.18231/j.ijpca.2023.020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The goal of cancer chemotherapy is to prevent or slow the growth of tumors by using various Biological or natural agents. Epidemiological and pre-clinical data indicate that phytochemicals can influence cell proliferation and cell cycle regulation, are typically involved in multiple signaling pathways that are frequently disrupted during tumour initiation, proliferation, and propagation, strengthen the host immune system, and make cancer cells more susceptible to cell-damaging agents. Only a small subset of these medicines have undergone clinical testing, and the results of those trials have been inconsistent, despite favorable outcomes from Experimental investigation. Recognizing the impact of these dietary changes may inspire easy and affordable solutions to improve health globally as the global rate of cancer continues to rise. In this article, we provide a summary of the information on a few phytochemicals with a particular focus on the clinical data demonstrating these compounds' effectiveness in populations at significant risk.\",\"PeriodicalId\":13889,\"journal\":{\"name\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijpca.2023.020\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry and Analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijpca.2023.020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The goal of cancer chemotherapy is to prevent or slow the growth of tumors by using various Biological or natural agents. Epidemiological and pre-clinical data indicate that phytochemicals can influence cell proliferation and cell cycle regulation, are typically involved in multiple signaling pathways that are frequently disrupted during tumour initiation, proliferation, and propagation, strengthen the host immune system, and make cancer cells more susceptible to cell-damaging agents. Only a small subset of these medicines have undergone clinical testing, and the results of those trials have been inconsistent, despite favorable outcomes from Experimental investigation. Recognizing the impact of these dietary changes may inspire easy and affordable solutions to improve health globally as the global rate of cancer continues to rise. In this article, we provide a summary of the information on a few phytochemicals with a particular focus on the clinical data demonstrating these compounds' effectiveness in populations at significant risk.