饮食中的植物化学物质和癌症化学预防

A. Sheikh, A. Arora, N. Chauhan
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引用次数: 0

摘要

癌症化疗的目的是通过使用各种生物或天然药物来防止或减缓肿瘤的生长。流行病学和临床前数据表明,植物化学物质可以影响细胞增殖和细胞周期调节,通常参与多种信号通路,这些信号通路在肿瘤发生、增殖和繁殖过程中经常被破坏,增强宿主免疫系统,使癌细胞更容易受到细胞损伤剂的影响。这些药物中只有一小部分经过了临床试验,尽管实验调查结果良好,但这些试验的结果却不一致。随着全球癌症发病率的持续上升,认识到这些饮食变化的影响可能会激发出简单和负担得起的解决方案,以改善全球健康。在这篇文章中,我们总结了一些植物化学物质的信息,特别关注临床数据,证明这些化合物在高危人群中的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dietary phytochemicals and cancer chemoprevention
The goal of cancer chemotherapy is to prevent or slow the growth of tumors by using various Biological or natural agents. Epidemiological and pre-clinical data indicate that phytochemicals can influence cell proliferation and cell cycle regulation, are typically involved in multiple signaling pathways that are frequently disrupted during tumour initiation, proliferation, and propagation, strengthen the host immune system, and make cancer cells more susceptible to cell-damaging agents. Only a small subset of these medicines have undergone clinical testing, and the results of those trials have been inconsistent, despite favorable outcomes from Experimental investigation. Recognizing the impact of these dietary changes may inspire easy and affordable solutions to improve health globally as the global rate of cancer continues to rise. In this article, we provide a summary of the information on a few phytochemicals with a particular focus on the clinical data demonstrating these compounds' effectiveness in populations at significant risk.
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