M. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk
{"title":"惠普尔氏病临床1例","authors":"M. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk","doi":"10.17816/mechnikov105632","DOIUrl":null,"url":null,"abstract":"The article presents a clinical case of 68-years old patient with a Whipples disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS periodic acid Schiff) foamy macrophages, highly specific for Whipples disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.","PeriodicalId":12949,"journal":{"name":"HERALD of North-Western State Medical University named after I.I. Mechnikov","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical case of Whipple’s disease\",\"authors\":\"M. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk\",\"doi\":\"10.17816/mechnikov105632\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The article presents a clinical case of 68-years old patient with a Whipples disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS periodic acid Schiff) foamy macrophages, highly specific for Whipples disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.\",\"PeriodicalId\":12949,\"journal\":{\"name\":\"HERALD of North-Western State Medical University named after I.I. Mechnikov\",\"volume\":\"16 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HERALD of North-Western State Medical University named after I.I. Mechnikov\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17816/mechnikov105632\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HERALD of North-Western State Medical University named after I.I. Mechnikov","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17816/mechnikov105632","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The article presents a clinical case of 68-years old patient with a Whipples disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS periodic acid Schiff) foamy macrophages, highly specific for Whipples disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.
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