唾液拉曼光谱研究方法综述

IF 5.4 2区 化学 Q1 INSTRUMENTS & INSTRUMENTATION
Mike Hardy, Liam Kelleher, Paulo de Carvalho Gomes, E. Buchan, H. Chu, P. Goldberg Oppenheimer
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引用次数: 19

摘要

利用拉曼光谱结合唾液是一种令人兴奋的新兴光谱-生物流体组合。在这篇综述中,我们总结了目前在这类研究中使用的方法,特别是唾液的收集、预处理和储存,以及使用的测量程序和拉曼参数。考虑到灵敏检测的需要,表面增强拉曼方法和化学计量技术也被研究。编制了变量的元分析。我们观察到各种各样的方法,并得出结论,方法的标准化和更广泛的验证拉曼唾液研究的进展是必要的。尽管如此,这些研究显示了在医疗保健、执法和法医等应用程序中提高速度、诊断准确性和便携式设备可能性的巨大希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Methods in Raman spectroscopy for saliva studies – a review
Abstract The use of Raman spectroscopy combined with saliva is an exciting emerging spectroscopy-biofluid combination. In this review, we summarize current methods employed in such studies, in particular the collection, pretreatment, and storage of saliva, as well as measurement procedures and Raman parameters used. Given the need for sensitive detection, surface-enhanced Raman methods are also surveyed, alongside chemometric techniques. A meta-analysis of variables is compiled. We observe a wide range of approaches and conclude that standardization of methods and progress to more extensive validation Raman-saliva studies is necessary. Nevertheless, the studies show tremendous promise toward the improvement of speed, diagnostic accuracy, and portable device possibilities in applications such as healthcare, law enforcement, and forensics.
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来源期刊
Applied Spectroscopy Reviews
Applied Spectroscopy Reviews 工程技术-光谱学
CiteScore
13.80
自引率
1.60%
发文量
23
审稿时长
1 months
期刊介绍: Applied Spectroscopy Reviews provides the latest information on the principles, methods, and applications of all the diverse branches of spectroscopy, from X-ray, infrared, Raman, atomic absorption, and ESR to microwave, mass, NQR, NMR, and ICP. This international, single-source journal presents discussions that relate physical concepts to chemical applications for chemists, physicists, and other scientists using spectroscopic techniques.
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