D. Yalcin, S. Ignak, I. E. Uluisik, Olida Cecen, M. Sonkaya, Ozlem UNAY-DEMİREL
{"title":"单中心评估COVID-19的生物标志物和严重程度","authors":"D. Yalcin, S. Ignak, I. E. Uluisik, Olida Cecen, M. Sonkaya, Ozlem UNAY-DEMİREL","doi":"10.5799/jmid.1175432","DOIUrl":null,"url":null,"abstract":"Objectives: The clinical course of COVID-19 ranges from mild to severe. The predictability of clinical outcomes gains importance in managing the disease. In this retrospective cohort study, we aimed to investigate the relationship between biomarker levels and the clinical severity of COVID-19. \nMethods: COVID-19 patients (n=618) admitted to a tertiary care hospital in Istanbul, Turkey were classified according to their clinical status using a scoring system designed by WHO. Laboratory parameters such as D-dimer, ferritin, and lymphocyte count levels were evaluated. In order to find out the relation between laboratory biomarkers and the severity of COVID-19, univariable and multivariable logistic regression analyses were used. \nResults: A positive correlation was found when WHO Score was compared with D-dimer levels (r=.508, p","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Biomarkers and Severity of COVID-19 in A Single Center\",\"authors\":\"D. Yalcin, S. Ignak, I. E. Uluisik, Olida Cecen, M. Sonkaya, Ozlem UNAY-DEMİREL\",\"doi\":\"10.5799/jmid.1175432\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives: The clinical course of COVID-19 ranges from mild to severe. The predictability of clinical outcomes gains importance in managing the disease. In this retrospective cohort study, we aimed to investigate the relationship between biomarker levels and the clinical severity of COVID-19. \\nMethods: COVID-19 patients (n=618) admitted to a tertiary care hospital in Istanbul, Turkey were classified according to their clinical status using a scoring system designed by WHO. Laboratory parameters such as D-dimer, ferritin, and lymphocyte count levels were evaluated. In order to find out the relation between laboratory biomarkers and the severity of COVID-19, univariable and multivariable logistic regression analyses were used. \\nResults: A positive correlation was found when WHO Score was compared with D-dimer levels (r=.508, p\",\"PeriodicalId\":16603,\"journal\":{\"name\":\"Journal of Microbiology and Infectious Diseases\",\"volume\":\"22 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Microbiology and Infectious Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5799/jmid.1175432\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Microbiology and Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5799/jmid.1175432","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of Biomarkers and Severity of COVID-19 in A Single Center
Objectives: The clinical course of COVID-19 ranges from mild to severe. The predictability of clinical outcomes gains importance in managing the disease. In this retrospective cohort study, we aimed to investigate the relationship between biomarker levels and the clinical severity of COVID-19.
Methods: COVID-19 patients (n=618) admitted to a tertiary care hospital in Istanbul, Turkey were classified according to their clinical status using a scoring system designed by WHO. Laboratory parameters such as D-dimer, ferritin, and lymphocyte count levels were evaluated. In order to find out the relation between laboratory biomarkers and the severity of COVID-19, univariable and multivariable logistic regression analyses were used.
Results: A positive correlation was found when WHO Score was compared with D-dimer levels (r=.508, p
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
