Nevus Simplex

ABSTRACT Nevus simplex, or salmon patch, is a benign vascular malformation seen in 30%–40% of infants. Most lesions are self-limiting, resolving spontaneously between the ages of 1 and 2 years. The most affected areas of the skin are the occiput and posterior neck; however, facial, scalp, and sacral involvement can also be seen. A nevus simplex must be differentiated from a port wine stain, as port wine stains are persistent and can be associated with genetic syndromes. Although sacral lesions can be common in nevus simplex complex, when associated with a second lumbosacral anomaly, further evaluation for underlying spinal dysraphism should be considered.