2型糖尿病研究简介与展望

D. Lu, Jin-Yu Che, N. Yarla, Hong Zhu, Tingren Lu, Bin Xu, Swathi Putta
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引用次数: 19

摘要

2型糖尿病(T2DM)的患病率在全球持续上升。2型糖尿病的患病率不仅存在于发展中国家,现在在发达国家也存在。相应地,由于全球患者数量的增加和经济负担的增加,2型糖尿病的治疗方法需要改变(更高的效率)。进入新千年,人类基因组研究的零碎路径(思想驱动)和指数增长都在迅速发展。基因表型翻译、现代诊断学、药理学、药物开发、中医、个体化医疗等都是这种变化的有希望的学科。临床降糖治疗、发病机制、药物开发管线等方面尤为突出。总之,本文提供了T2DM的总体概况和原则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Type 2 Diabetes Study, Introduction and Perspective
The prevalence of Type 2 Diabetes Mellitus (T2DM) continues to rise globally. The T2DM prevalence is not only in developing countries, but also in developed countries now. Correspondingly, the therapeutics of T2DM calls for a change (higher efficiency) due to growing number of patients and increasing economic burdens globally. Entering into this millennium, both piecemeal pathways (idea driven) and exponential growth of human genomic study are developing quickly. Genetypic-phenotypic translation, modern diagnostics, pharmacology, drug developments, traditional Chinese medicine, personalized medicine and so on are promising disciplines for this change. The clinical anti-diabetic therapeutics, pathogenesis, drug development pipelines are especially highlighted.In summary, a general landscape and principle of T2DM is provided.
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