冷冻治疗在埃及中央气道阻塞患者:对临床肺评分、肺功能测试和生活质量的影响,单中心经验

IF 0.2 Q4 RESPIRATORY SYSTEM
A. Halfawy, H. Amin, Muhammad Younis, U. Elhassan
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引用次数: 0

摘要

冷冻治疗已成为治疗中央气道阻塞(CAO)患者的一种有效方法。目的是评估使用冷冻疗法治疗曹操的结果及其对曹操患者症状和肺功能测试(PFT)的影响。该前瞻性方案在开罗大学医院胸科与军事胸科医院合作进行,为期6个月。CAO患者接受冷冻治疗,并通过以下指标进行评估:气道阻塞程度、呼吸困难、咯血和生活质量评分,以及PFT。评估冷冻治疗的结果和安全性。结果共纳入30例曹操患者,分为恶性梗阻组(n=20)和非恶性梗阻组(n=10)。53.3%的患者完全恢复气道通畅。只有3例(10%)出现并发症。术后呼吸困难、咳嗽、咯血、生活质量量表和PFT均有显著改善。Logistic回归分析显示,吸烟与较差的预后相关。结论冷冻治疗对支气管内外生性肿瘤和非恶性曹化气均是安全有效的治疗方法。这些益处反映在术后临床肺评分、PFT、气道阻塞等级和生活质量的改善上。建议进一步开展前瞻性、多中心研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cryotherapy in Egyptian patients with central airway obstruction: impacts on clinical pulmonary scores, pulmonary function tests and quality of life, a single center experience
Background Cryotherapy has emerged as an effective modality to manage patients with central airway obstruction (CAO). The aim was to assess the outcomes of using cryotherapy for managing CAO and its effect on the symptoms, and pulmonary function testing (PFT) in patients with CAO. Patients and methods This prospective protocol was carried out at the Chest Department, Cairo University Hospitals, in collaboration with the Military Chest Hospital over 6 months. Patients with CAO underwent cryotherapy and were assessed by the following: grade of airway obstruction, dyspnea, hemoptysis and quality of life scales, and PFT. Outcomes and safety of cryotherapy were evaluated. Results A total of 30 patients with CAO were enrolled and were divided into two groups: the malignant obstruction group (n=20) and the nonmalignant obstruction group (n=10). Complete restoration of the airway patency was achieved in 53.3% of patients. Only three (10%) cases encountered complications. There were significant postprocedural improvements of dyspnea, cough, hemoptysis, quality of life scales, and PFT. Logistic regression analysis showed that smoking was associated with worse outcomes. Conclusions Cryotherapy is a safe and successful method for both endobronchial exophytic tumor debulking and nonmalignant CAO. These benefits were reflected in the postprocedural improvement of clinical pulmonary scales, PFT, the grade of airway obstruction, and quality of life. Further prospective, multicenter studies are recommended.
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来源期刊
自引率
0.00%
发文量
46
审稿时长
22 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of The Egyptian Journal of Chest Diseases and Tuberculosis aims to publish and inform readers and all chest physicians of the progress in medical research concerning all aspect of chest diseases. Publications include original articles review articles, editorials, case studies and reports which are relevant to chest diseases. The Journal also aims to highlight recent updates in chest medicine. . Articles with clinical interest and implications will be given preference.
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