拉丁美洲性别对多系统炎症综合征和covid-19儿童疾病严重程度的影响

Q3 Social Sciences

Italian Journal of Gender-Specific Medicine Pub Date : 2021-01-01 DOI:10.1723/3673.36590

M. Brizuela, J. Lenzi, R. Ulloa-Gutiérrez, O. Antúnez-Montes, J. Aida, O. del Águila, E. Arteaga-Menchaca, F. Campos, F. Uribe, A. P. Buitrago, L. M. B. Londoño, J. Gómez-Vargas, A. Yock-Corrales, D. Buonsenso

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引用次数: 3

摘要

成人研究数据显示，COVID-19在男性中比女性更严重。然而，没有关于儿科人群的数据。出于这个原因，我们进行了这项研究，旨在了解性别是否影响拉丁美洲患有COVID-19和多系统炎症综合征(MIS-C)的儿童的疾病严重程度和结局。我们发现，男童患misc的比例较高(8.9%对5%的女性)和死亡(1.2%对0.4%的女性)，尽管在多变量调整分析中，唯一有统计学意义的差异是需要住院治疗，与男童相比，女童住院的频率较低(25.6%对35.4%)。这些数据是初步的，需要进一步的独立研究来更好地评估性别的作用。©2021,Il Pensiero Scientifico Editore s.r.l。版权所有。

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Influence of sex on disease severity in children with multisystem inflammatory syndrome and covid-19 in latin america

Data from adult studies show that COVID-19 is more severe in men than women. However, no data are available for the pediatric population. For this reason, we performed this study aiming to understand if sex influenced disease severity and outcomes in a large cohort of Latin-American children with COVID-19 and multisystem inflammatory syndrome (MIS-C). We found that a higher percentage of male children developed MIS-C (8.9% vs 5% in females) and died (1.2% and 0.4% in females), although on multivariate adjusted analyses the only statistically significant difference was found in need of hospitalization, with females less frequently admitted compared with boys (25.6% vs 35.4%). This data are preliminary and need further independent studies to better assess the role of sex. © 2021, Il Pensiero Scientifico Editore s.r.l.. All rights reserved.

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来源期刊

Italian Journal of Gender-Specific Medicine Social Sciences-Gender Studies

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