离子电泳给药研究进展

M. Dehghan, Md. Ismail Mouzam
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引用次数: 13

摘要

离子电泳是一项令人兴奋的技术,最初是在250年前研究的。简单地说,它是一种电势的应用,可以在皮肤或屏障上保持恒定的电流,从而增强电离和非电离部分的传递。在过去的几年里,不同类型的离子导入,如经皮、眼、经口、口腔、硬脑膜和经鼻离子导入已被报道。每个系统都有自己的优点和缺点。本文综述了近年来各种离子电泳技术的研究进展及其应用。关键词:电离子透入疗法;皮肤;眼;颊;transungual;乌拉尔;药物输送。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in iontophoresis for drug delivery
Iontophoresis is an exciting technology that was initially investigated 250 years ago. Simply defined, it is the application of an electrical potential that maintains a constant electric current across the skin or barrier that enhances the delivery of ionized as well as unionized moieties. In the past few years, different types of iontophoresis such as transdermal, ophthalmic, transungual, buccal, ural and transnasal iontophoresis have been reported. Each system has its own advantages and drawbacks. The review summarizes recent findings and applications of various iontophoresis techniques. Keywords: Iontophoresis; transdermal; ocular; buccal; transungual; ural; drug delivery.
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