真单细胞化学分析在癌症研究中的应用综述

Karen Reyes, G. Verbeck
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引用次数: 0

摘要

真单细胞(TOC)分析在癌细胞的功能研究中变得越来越重要。这部分是因为它是唯一的分析形式,为研究单个癌细胞的异质性和细胞间变异提供了途径,从而为控制肿瘤内TOC功能的复杂调节过程提供了独特的见解。此外,真正的单细胞技术在当前尝试实施TOC代谢组学和蛋白质组学研究以及空间解析TOC信息的新尝试中发挥着越来越重要的作用。本文简要介绍了该领域的基础,并讨论了其在TOC代谢组学和蛋白质组学中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
True One Cell Chemical Analysis in Cancer Research: A Review
True One Cell (TOC) analysis Is becoming highly critical for functional studies of cancer cells. This is partially because it is the only form of analysis that provides an avenue for studying the heterogeneity and cell-to-cell variations of individual cancer cells, thus providing unique insight into complex regulatory processes that govern TOC functions within a tumor. Additionally, true one cell techniques are playing an increasingly important role in current attempts to implement TOC metabolomic and proteomic studies, as well as emerging attempts to spatially resolve TOC information. In this review we provide a brief overview of the basis of the field and discuss its applications in TOC metabolomics and proteomics.
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