Claudia Sievers, Benedikt Zacher, Alexander Ullrich, Matthew Huska, Stephan Fuchs, Silke Buda, Walter Haas, Michaela Diercke, Matthias An der Heiden, Stefan Kröger
{"title":"与德国 2021 年至 2022 年的德尔塔相比，SARS-CoV-2 Omicron 变体 BA.1 和 BA.2 都显示 COVID-19 的疾病严重程度同样有所降低。","authors":"Claudia Sievers, Benedikt Zacher, Alexander Ullrich, Matthew Huska, Stephan Fuchs, Silke Buda, Walter Haas, Michaela Diercke, Matthias An der Heiden, Stefan Kröger","doi":"10.2807/1560-7917.ES.2022.27.22.2200396","DOIUrl":null,"url":null,"abstract":"<p><p>German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.</p>","PeriodicalId":53382,"journal":{"name":"The Bible and Critical Theory","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164675/pdf/","citationCount":"0","resultStr":"{\"title\":\"SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022.\",\"authors\":\"Claudia Sievers, Benedikt Zacher, Alexander Ullrich, Matthew Huska, Stephan Fuchs, Silke Buda, Walter Haas, Michaela Diercke, Matthias An der Heiden, Stefan Kröger\",\"doi\":\"10.2807/1560-7917.ES.2022.27.22.2200396\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.</p>\",\"PeriodicalId\":53382,\"journal\":{\"name\":\"The Bible and Critical Theory\",\"volume\":\"5 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164675/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Bible and Critical Theory\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2807/1560-7917.ES.2022.27.22.2200396\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Bible and Critical Theory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2807/1560-7917.ES.2022.27.22.2200396","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022.
German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.
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