M. Abdelnaby, Ahmed M. Ibrahim, Muhammad Mahmoud Abdul Haleem
{"title":"急性哌乙酯HCl (Selgon, Eipico Egypt, Egypt)毒性:病例报告","authors":"M. Abdelnaby, Ahmed M. Ibrahim, Muhammad Mahmoud Abdul Haleem","doi":"10.4172/2161-0495.1000356","DOIUrl":null,"url":null,"abstract":"Pipazethate HCl is a centrally acting non-narcotic antitussive which is infrequently used nowadays. The toxicity of this drug is rarely reported in the literature. We were encountered with a case of accidental ingestion of Pipazethate HCl in a 3-years-old child presented with neurological symptoms in the form of somnolence, disturbed sensorium, respiratory symptoms in the form of respiratory distress and cardiac dysrhythmias in the form of Torsade de pointes. The patient was managed at a critical care unit using supportive measures for neurological symptoms, shock state and respiratory distress. Arrhythmic complications were managed using magnesium sulphate and maintained on lidocaine infusion. After two days under observation, the child was discharged home safely.","PeriodicalId":15433,"journal":{"name":"Journal of Clinical Toxicology","volume":"7 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Acute Pipazethate HCl (Selgon, Eipico Egypt, Egypt) Toxicity: Case Report\",\"authors\":\"M. Abdelnaby, Ahmed M. Ibrahim, Muhammad Mahmoud Abdul Haleem\",\"doi\":\"10.4172/2161-0495.1000356\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pipazethate HCl is a centrally acting non-narcotic antitussive which is infrequently used nowadays. The toxicity of this drug is rarely reported in the literature. We were encountered with a case of accidental ingestion of Pipazethate HCl in a 3-years-old child presented with neurological symptoms in the form of somnolence, disturbed sensorium, respiratory symptoms in the form of respiratory distress and cardiac dysrhythmias in the form of Torsade de pointes. The patient was managed at a critical care unit using supportive measures for neurological symptoms, shock state and respiratory distress. Arrhythmic complications were managed using magnesium sulphate and maintained on lidocaine infusion. After two days under observation, the child was discharged home safely.\",\"PeriodicalId\":15433,\"journal\":{\"name\":\"Journal of Clinical Toxicology\",\"volume\":\"7 1\",\"pages\":\"1-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2161-0495.1000356\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2161-0495.1000356","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Acute Pipazethate HCl (Selgon, Eipico Egypt, Egypt) Toxicity: Case Report
Pipazethate HCl is a centrally acting non-narcotic antitussive which is infrequently used nowadays. The toxicity of this drug is rarely reported in the literature. We were encountered with a case of accidental ingestion of Pipazethate HCl in a 3-years-old child presented with neurological symptoms in the form of somnolence, disturbed sensorium, respiratory symptoms in the form of respiratory distress and cardiac dysrhythmias in the form of Torsade de pointes. The patient was managed at a critical care unit using supportive measures for neurological symptoms, shock state and respiratory distress. Arrhythmic complications were managed using magnesium sulphate and maintained on lidocaine infusion. After two days under observation, the child was discharged home safely.