PCOS患者高催乳素血症的频率及其与女性不育的关系

Anam Rehman
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引用次数: 0

摘要

不孕不育是一个关键的健康问题,部分原因是其原因复杂,努力预防,诊断和治疗。多项研究证明多囊卵巢综合征与高催乳素血症之间存在密切联系。目的和目的:本研究旨在确定PCOS患者高泌乳素血症的频率及其与不孕症的关系。研究地点和持续时间:这是一项横断面研究,于2017年4月至2017年9月在巴基斯坦费萨拉巴德的AzizFatimah医院进行。材料与方法:这是一项横断面研究,于2017年4月至9月在巴基斯坦费萨拉巴德的阿齐兹法蒂玛医院进行。本研究由88名17-35岁的女性受试者组成,其中包括多囊卵巢综合征受试者和年龄匹配的对照组。采用化学发光免疫分析法(CLIA)测定血清催乳素水平,评价高催乳素血症。采用SPSS version 22对数据进行统计分析。结果:在总共88名女性参与者中,61.4%的多囊卵巢综合征患者患有高催乳素血症,而对照组的这一比例为36.4%。Pearson相关性也显示高泌乳素血症与不孕症有显著正相关。结论:多囊卵巢综合征患者高泌乳素血症发生率高,BMI升高。催乳素水平升高与女性不育密切相关。关键词:高泌乳素血症,不孕症,多囊卵巢综合征
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency of Hyperprolactinemia in PCOS and its Association with Female Infertility
Introduction: Infertility is a critical health concern partially due to intricacy in its causes and striving for its prevention, diagnosis and treatment. Various researches have documented a close linkage between polycystic ovary syndrome and hyperprolactinemia. Aims & Objectives: This study was aimed to determine the frequency of hyperprolactinemia in PCOS and its association with infertility in PCOS subjects. Place and duration of study: It was a cross sectional study, conducted during April 2017 and September 2017 at Aziz Fatimah Hospital, Faisalabad, Pakistan. Material & Methods: It was a cross sectional study which was conducted at Aziz Fatimah Hospital, Faisalabad, Pakistan from April to September 2017. This study comprised of 88 female subjects of 17-35 years old who included PCOS subjects and age matched controls. Hyperprolactinemia was assessed by the measurement of serum prolactin levels which were measured by chemiluminescence immunoassay technique (CLIA). SPSS version 22 was used for the statistical analysis of the data. Results: Out of total 88 female participants, 61.4% of polycystic ovary syndrome subjects had hyperprolactinemia as compared to this 36.4% of controls had hyperprolactinemia. Pearson correlation also revealed significant positive association of hyperprolactinemia with infertility. Conclusion: Hyperprolactinemia was frequently seen in polycystic ovary syndrome females as well as raised BMI was also found. Raised prolactin levels are strongly associated with female infertility. Key words: Hyperprolactinemia, Infertilty, Polycystic Ovary Syndrome.
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