A. Oral, F. Solano, A. Crimaldi, D. Salamon, M.V. Griffin
{"title":"静脉注射大剂量免疫球蛋白治疗输血后紫癜——结合血小板和游离血小板抗体的变化及植物血凝素体外淋巴细胞转化的变化","authors":"A. Oral, F. Solano, A. Crimaldi, D. Salamon, M.V. Griffin","doi":"10.1016/0278-6222(88)90016-2","DOIUrl":null,"url":null,"abstract":"<div><p>A middle-aged female with posttransfusion purpura (PTP), serologically proven to be associated with anti-PLAI antibody was treated successfully with high-dose intravenous immunoglobulin (IVIG). Normalization of the Platelet Associated IgG-antibody (PAIgG) correlated with peak platelet count on day 6 of therapy. Anti-PLAI antibody was detectable until week 5 of the follow-up period. Impaired pre-therapy lymphocyte transformation with Phytohemagglutinin (PHA) corrected with the disappearance of the Anti-PLAI antibody.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 4","pages":"Pages 359-363"},"PeriodicalIF":0.0000,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90016-2","citationCount":"0","resultStr":"{\"title\":\"High dose intravenous immunoglobulin in post transfusion purpura—Changes in bound and free platelet antibody and in vitro lymphocyte transformation with Phytohemagglutinin\",\"authors\":\"A. Oral, F. Solano, A. Crimaldi, D. Salamon, M.V. Griffin\",\"doi\":\"10.1016/0278-6222(88)90016-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A middle-aged female with posttransfusion purpura (PTP), serologically proven to be associated with anti-PLAI antibody was treated successfully with high-dose intravenous immunoglobulin (IVIG). Normalization of the Platelet Associated IgG-antibody (PAIgG) correlated with peak platelet count on day 6 of therapy. Anti-PLAI antibody was detectable until week 5 of the follow-up period. Impaired pre-therapy lymphocyte transformation with Phytohemagglutinin (PHA) corrected with the disappearance of the Anti-PLAI antibody.</p></div>\",\"PeriodicalId\":101030,\"journal\":{\"name\":\"Plasma Therapy and Transfusion Technology\",\"volume\":\"9 4\",\"pages\":\"Pages 359-363\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0278-6222(88)90016-2\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plasma Therapy and Transfusion Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0278622288900162\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasma Therapy and Transfusion Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0278622288900162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
High dose intravenous immunoglobulin in post transfusion purpura—Changes in bound and free platelet antibody and in vitro lymphocyte transformation with Phytohemagglutinin
A middle-aged female with posttransfusion purpura (PTP), serologically proven to be associated with anti-PLAI antibody was treated successfully with high-dose intravenous immunoglobulin (IVIG). Normalization of the Platelet Associated IgG-antibody (PAIgG) correlated with peak platelet count on day 6 of therapy. Anti-PLAI antibody was detectable until week 5 of the follow-up period. Impaired pre-therapy lymphocyte transformation with Phytohemagglutinin (PHA) corrected with the disappearance of the Anti-PLAI antibody.
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