异维甲酸在痤疮治疗中的作用机制假说

Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology) Pub Date : 2022-07-30 DOI:10.33920/med-13-2208-06

A. G. Okhtyarkina

{"title":"异维甲酸在痤疮治疗中的作用机制假说","authors":"A. G. Okhtyarkina","doi":"10.33920/med-13-2208-06","DOIUrl":null,"url":null,"abstract":"Currently, the problem of acne does not lose its relevance not only among adolescents, but also in adult women and men. One of the most effective drugs in the treatment of severe and resistant forms of acne are isotretinoin preparations, i.e. systemic retinoids, the instructions for which do not indicate the mechanism of action. The purpose of the work: to consider the hypotheses of the mechanism of action of systemic retinoids on various pathogenetic acne factors.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"85 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hypotheses for isotretinoin mechanisms of action in acne treatment\",\"authors\":\"A. G. Okhtyarkina\",\"doi\":\"10.33920/med-13-2208-06\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Currently, the problem of acne does not lose its relevance not only among adolescents, but also in adult women and men. One of the most effective drugs in the treatment of severe and resistant forms of acne are isotretinoin preparations, i.e. systemic retinoids, the instructions for which do not indicate the mechanism of action. The purpose of the work: to consider the hypotheses of the mechanism of action of systemic retinoids on various pathogenetic acne factors.\",\"PeriodicalId\":12259,\"journal\":{\"name\":\"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)\",\"volume\":\"85 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33920/med-13-2208-06\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33920/med-13-2208-06","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

目前，痤疮问题不仅在青少年中，而且在成年女性和男性中也没有失去其相关性。治疗严重和耐药型痤疮最有效的药物之一是异维甲酸制剂，即全身类维甲酸，说明书上没有说明其作用机制。研究目的:探讨系统性类维生素a对痤疮各种致病因素作用机制的假说。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Hypotheses for isotretinoin mechanisms of action in acne treatment

Currently, the problem of acne does not lose its relevance not only among adolescents, but also in adult women and men. One of the most effective drugs in the treatment of severe and resistant forms of acne are isotretinoin preparations, i.e. systemic retinoids, the instructions for which do not indicate the mechanism of action. The purpose of the work: to consider the hypotheses of the mechanism of action of systemic retinoids on various pathogenetic acne factors.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)

自引率

0.00%

发文量