基尔库克市流产妇女中人乳头瘤病毒的血清流行率

Jacklen Zaea Khoshaba, S. Mustafa, Muhannad Abdulla Alazzawy
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摘要

该研究的目的是评估人乳头瘤病毒(HPV)在流产妇女的血清患病率。2017年3月10日至2017年7月10日在基尔库克市进行了一项横断面研究,在基尔库克综合医院接受刮除术的流产妇女人数为65名。与研究患者相匹配的对照组包括30名正常足月妊娠妇女,刚地弓形虫、风疹和巨细胞病毒感染妇女排除在研究之外。采用静脉穿刺法采集患者血清5 ml,分别用ELISA技术检测患者和对照组的HPV 16e7蛋白。研究显示,人工流产妇女的HPV感染率最高,为35.38%,与对照组有高度显著的相关性。研究表明,75.38%的妇女在妊娠前三个月流产,最后三个月流产率最低,为9.24%。研究表明,HPV感染率最高的是流产前3个月(38.78%),最低的是流产后3个月。研究表明,在婚姻生活中经历过一次堕胎的堕胎妇女中,HPV感染率最高。结论:在妊娠前三个月流产的妇女中,HPV与流产有显著的空间关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seroprevalence of Human Papilloma Virus in Aborted Women in Kirkuk City
The aimed of the study was to evaluate the Seroprevalence of human papilloma virus (HPV) in aborted women. A cross-sectional study was carried out in Kirkuk city from 10th of March 2017 to 10th of July 2017 The number of aborted women understudy were 65 women who attended for curettage in Kirkuk general hospital. The control group who were matched to the patients studied included 30 normal pregnant women at the full term of pregnancy, women with Toxoplasma gondii , rubella and cytomegalovirus infections were excluded from the study. Five ml of blood was collected by vein puncture from each woman in the study, the obtained sera then organized to determine of HPV 16 E7 protein in patients and control using ELISA technique. The study showed that the highest rate of HPV infection (35.38%) was recorded among women with abortion comparing with the control group, with a highly significant relation. The study showed that 75.38% of women had aborted in the 1st trimester of pregnancy and the lowest rate of abortion 9.24% was in the 3rd trimester. The study showed that the highest rate of HPV infection was found in women with 1st trimester of abortion (38.78%) and the lowest rate was in the 3rd trimester of abortion. The study showed that the highest rate of HPV infection was recorded among aborted women who have suffered from one abortion during their marriage life. It was concluded that there was a significant relation of HPV with abortion spatially in women who were aborted in the first trimester of pregnancy.
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