口服控释给药系统及口服片剂的表征回顾

M. Zaman, Junaid Qureshi, Hira Ejaz, R. M. Sarfraz, H. Khan, Fazal Rehman Sajid, M. A. U. Rehman
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引用次数: 16

摘要

口服给药途径被认为是最安全、最简便的给药途径。控释给药系统是药物领域的发展趋势,口服给药是最适合这种给药系统的途径。口服途径更方便所有年龄组,包括儿童和老年人。有各种不同的系统,通过口服途径以受控的方式将药物递送到不同的靶点。它包括扩散控制的药物输送系统;溶出控制给药系统、渗透控制给药系统、离子交换控制给药系统、流体动力学平衡系统、多颗粒给药系统和微囊化给药系统。该系统采用不同的天然、半合成和合成聚合物配制而成。这篇综述的目的是提供关于口服控制给药系统的信息,用于配制这些系统的聚合物以及最方便的剂型之一即片剂的特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oral controlled release drug delivery system and Characterization of oral tablets; A review
Oral route of drug administration is considered as the safest and easiest route of drug administration. Control release drug delivery system is the emerging trend in the pharmaceuticals and the oral route is most suitable for such kind of drug delivery system. Oral route is more convenient for It all age group including both pediatric and geriatrics. There are various systems which are adopted to deliver drug in a controlled manner to different target sites through oral route. It includes diffusion controlled drug delivery systems; dissolution controlled drug delivery systems, osmotically controlled drug delivery systems, ion-exchange controlled drug delivery systems, hydrodynamically balanced systems, multi-Particulate drug delivery systems and microencapsulated drug delivery system. The systems are formulated using different natural, semi-synthetic and synthetic polymers. The purpose of the review is to provide information about the orally controlled drug delivery system, polymers which are used to formulate these systems and characterizations of one of the most convenient dosage form which is the tablets.
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