石竹精油的化学成分及脂氧合酶抑制活性研究

IF 0.5 Q4 CHEMISTRY, MULTIDISCIPLINARY

Chemistry Journal of Moldova Pub Date : 2021-12-01 DOI:10.19261/cjm.2021.848

Wan Mohd Nuzul Hakimi Wan Salleh, M. Nadri, S. Khamis

{"title":"石竹精油的化学成分及脂氧合酶抑制活性研究","authors":"Wan Mohd Nuzul Hakimi Wan Salleh, M. Nadri, S. Khamis","doi":"10.19261/cjm.2021.848","DOIUrl":null,"url":null,"abstract":"This study was aimed to investigate the chemica l compositions and lipoxygenase inhibitory activity of the essential oil from Alstonia angustiloba growing in Malaysia. The essential oils were obtained by hydrodistillation and fully characterized by gas chromatography and gas chromatography-mass spectrometry. Analysis of the A. angustiloba essential oil resulted in the identification of twenty-five chemical components, attributed 90.8% of the total oil. The most abundant components of A. angustiloba oil were linalool (21.2%), 1,8-cineole (16.8%), α-terpineol (9.5%), terpinene-4-ol (8.5%), β-caryophyllene (6.2%), and caryophyllene oxide (5.2%). The essential oil displayed moderate activity towards lipoxygenase activity with IC50 value of 45.8 μg/mL.","PeriodicalId":9922,"journal":{"name":"Chemistry Journal of Moldova","volume":"206 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemical Composition and Lipoxygenase Inhibitory Activity of the Essential Oil of Alstonia Angustiloba\",\"authors\":\"Wan Mohd Nuzul Hakimi Wan Salleh, M. Nadri, S. Khamis\",\"doi\":\"10.19261/cjm.2021.848\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was aimed to investigate the chemica l compositions and lipoxygenase inhibitory activity of the essential oil from Alstonia angustiloba growing in Malaysia. The essential oils were obtained by hydrodistillation and fully characterized by gas chromatography and gas chromatography-mass spectrometry. Analysis of the A. angustiloba essential oil resulted in the identification of twenty-five chemical components, attributed 90.8% of the total oil. The most abundant components of A. angustiloba oil were linalool (21.2%), 1,8-cineole (16.8%), α-terpineol (9.5%), terpinene-4-ol (8.5%), β-caryophyllene (6.2%), and caryophyllene oxide (5.2%). The essential oil displayed moderate activity towards lipoxygenase activity with IC50 value of 45.8 μg/mL.\",\"PeriodicalId\":9922,\"journal\":{\"name\":\"Chemistry Journal of Moldova\",\"volume\":\"206 1\",\"pages\":\"\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry Journal of Moldova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.19261/cjm.2021.848\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry Journal of Moldova","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19261/cjm.2021.848","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

本研究旨在研究生长在马来西亚的紫檀精油的化学成分和脂氧合酶抑制活性。采用水蒸气蒸馏法得到精油，并采用气相色谱法和气相色谱-质谱法对其进行了表征。结果表明，经分析鉴定出25种化学成分，占总挥发油的90.8%。油中含量最高的成分为芳樟醇(21.2%)、1,8-桉叶油素(16.8%)、α-松油醇(9.5%)、松油烯-4-醇(8.5%)、β-石竹烯(6.2%)和石竹烯氧化物(5.2%)。挥发油对脂氧合酶活性具有中等活性，IC50值为45.8 μg/mL。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Chemical Composition and Lipoxygenase Inhibitory Activity of the Essential Oil of Alstonia Angustiloba

This study was aimed to investigate the chemica l compositions and lipoxygenase inhibitory activity of the essential oil from Alstonia angustiloba growing in Malaysia. The essential oils were obtained by hydrodistillation and fully characterized by gas chromatography and gas chromatography-mass spectrometry. Analysis of the A. angustiloba essential oil resulted in the identification of twenty-five chemical components, attributed 90.8% of the total oil. The most abundant components of A. angustiloba oil were linalool (21.2%), 1,8-cineole (16.8%), α-terpineol (9.5%), terpinene-4-ol (8.5%), β-caryophyllene (6.2%), and caryophyllene oxide (5.2%). The essential oil displayed moderate activity towards lipoxygenase activity with IC50 value of 45.8 μg/mL.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemistry Journal of Moldova CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

0.90

自引率

20.00%

发文量

审稿时长

12 weeks

期刊介绍： "Chemistry Journal of Moldova. General, Industrial and Ecological Chemistry" seeks to publish experimental or theoretical research results of outstanding significance and timeliness in all fields of Chemistry, including Industrial and Ecological Chemistry. The main goal of this edition is strengthening the Chemical Society of Moldova, following development of research in Moldovan chemical institutions and promotion of their collaboration with international chemical community. Manuscripts are welcome from all countries.