乳腺原发性血管肉瘤:一系列病例的临床病理和影像学研究

IF 1.8 Q3 ONCOLOGY

Breast Cancer : Basic and Clinical Research Pub Date : 2022-01-01 DOI:10.1177/11782234221086726

T. Darré, Toukilnan Djiwa, B. N’timon, P. Simgban, Mazamaesso Tchaou, G. Napo-koura

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引用次数: 5

摘要

我们研究的目的是提供乳腺原发性血管肉瘤的临床病理和影像学特征。我们回顾性分析了20年间(2000-2019年)在lomoise病理实验室诊断的原发性血管肉瘤病例。本文收集了8例原发性乳腺血管肉瘤，其中女性6例，男性2例。年龄中位数为41.63岁(17 ~ 66岁)。根据位置不同，8例中有4例发生在左乳房。超声分级为BI-RADS 4、5。组织学显示恶性血管增生，由非典型内皮细胞排列的小管腔，明显的有丝分裂和坏死灶组成。免疫组化结果显示，病变细胞表达CD31、CD34和因子VIII。根据全国癌症控制中心联合会(FNCLCC)的分级，病例分为II级和III级。女性患者6个月的总生存率估计为25%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Breast Primary Angiosarcoma: A Clinicopathologic and Imaging Study of a Series Cases

The aim of our study is to provide clinicopathologic and imaging features of breast primary angiosarcoma. We retrospectively analyzed cases of primary angiosarcoma diagnosed at the Pathological Laboratory of Lomé over a period of 20 years (2000-2019). Eight cases of primary angiosarcoma of the breast were collected, including 6 from women and 2 from men. The median age was 41.63 years (range from 17 to 66 years). Depending on the location, there were 4 of 8 cases in the left breast. Ultrasound classifications were BI-RADS 4 and 5. Histology revealed a malignant vascular proliferation composed of small lumens lined by atypical endothelial cells, evident mitoses, and foci of necrosis. On immunohistochemistry, the lesional cells expressed CD31, CD34, and Factor VIII. Based on Federation Nationale des Centers de Lutte Contre Le Cancer (FNCLCC) grading, the cases were grade II and III. Overall survival at 6 months was estimated to be 25% in a woman.

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来源期刊

Breast Cancer : Basic and Clinical Research ONCOLOGY-

CiteScore

5.10

自引率

3.40%

发文量

审稿时长

8 weeks

期刊介绍： Breast Cancer: Basic and Clinical Research is an international, open access, peer-reviewed, journal which considers manuscripts on all areas of breast cancer research and treatment. We welcome original research, short notes, case studies and review articles related to breast cancer-related research. Specific areas of interest include, but are not limited to, breast cancer sub types, pathobiology, metastasis, genetics and epigenetics, mammary gland biology, breast cancer models, prevention, detection, therapy and clinical interventions, and epidemiology and population genetics.