世界卫生组织药敏试验在尼日利亚东南部用于疟疾病媒控制的论述

J. Akilah, I. Ekong
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引用次数: 0

摘要

背景:随着越来越多的证据表明蚊子媒介对拟除虫菊酯类杀虫剂和其他种类杀虫剂产生抗药性,我们采用了两种重要工具之一,通过世界卫生组织(世卫组织)的药敏试验,在尼日利亚东南部选定的州监测杀虫剂抗药性。目的:本研究检验了世卫组织药敏试验在尼日利亚用于鉴定和监测传播疟疾和虫媒病毒相关疾病的按蚊和伊蚊耐药性的有效性。方法:采用诱蚊诱卵器在不同研究地点进行蚊幼虫取样;鸡蛋被孵化和饲养,随后根据世卫组织测试程序进行敏感性测试。摘要与结论:对二氯二苯三氯乙烷和拟除虫菊酯的抗性已在很大程度上确立。拟除虫菊酯功效的丧失可能导致疾病控制计划的操作失败。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of World Health Organization susceptibility test for malaria vector control in South-Eastern Nigeria: A discourse
Background: With growing evidence of mosquito vector resistance to pyrethroids and other classes of insecticides globally, we employed one of the two important tools for the monitoring of insecticide resistance in selected states in southeastern part of Nigeria via the World Health Organization (WHO) susceptibility test. Aim: This study tested the effectiveness of WHO susceptibility test for the use in identifying and monitoring the resistance of Anopheles and Aedes mosquitoes which transmit malaria and arbovirus-related diseases in Nigeria. Methods: Larval sampling of mosquitoes was embarked upon with ovitraps set in various study sites; eggs were hatched and reared and subsequently subjected to susceptibility tests according to the WHO test procedures. Summary and Conclusion: Resistance to dichloro diphenyl trichloroethane and the pyrethroids has been established to a large extent. The loss of efficacy of pyrethroids may result in operational failure of disease control programs.
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