Eucalyptus camaldulensis efficiency for application against microbial infections

On account of the continuing increase in antimicrobial resistance among infectious agents which are mostly life-threatening, seeking novel and alternative therapeutic approaches seems essential. Eucalyptus camaldulensis, generally known as eucalyptus, contains various healing traits such as antimicrobial characteristics. These herbs generally grow alongside the rivers with both continuous and seasonal water. The antimicrobial applications of this herb, particularly against pandrug and multidrug resistant microorganisms mostly attributed to phenolic, polar terpene compounds and spathulenol. Major bioactive antimicrobial fractions include flavonoids, alkaloids, pigments, terpenes, phenolics, starches, steroids and essential oils. E. camaldulensis has antimicrobial features against various bacterial (both Gram-positive and Gram-negative species), fungal, parasitic and viral infections. Regarding molecular mechanisms, the discharge of Gram-negative outer membrane lipopolysaccharide and increase the permeability of the cytoplasmic membrane have been proposed. Leaf extracts might be a good source of antibacterial and antifungal materials that might be useful in pharmaceutical industry. Interactions with various conventional antimicrobial agents providing synergistic effects suppose a variety of antimicrobial mechanisms by fractions remaining to be entirely elucidated.