大蒜乙醇提取物在海藻酸盐压印材料中对白色念珠菌生长的抑制作用

Dendy Murdiyanto, Aryani Faizah, Mandira Dhaksi Mustikaningrum
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引用次数: 0

摘要

藻酸盐是目前用于牙科的印模材料,因为它有许多优点。然而,海藻酸盐在使用过程中会直接接触血液、唾液和斑块。因此,它有可能含有致病微生物。白色念珠菌是其中一种具有致病性的微生物。它可以感染口腔并引起念珠菌病。因此,有必要以大蒜(Allium sativum L.)中的天然成分的形式抑制白色念珠菌的生长。大蒜(Allium sativum L.)具有抗真菌的功效,因为它含有一种活性成分,即大蒜素。目的是考察大蒜(Allium sativum L.)乙醇提取物作为海藻酸盐印模材料的溶剂对白色念珠菌生长的抑制作用。研究方法为海藻酸盐操作圆盘扩散,以蒸馏水为溶剂,大蒜乙醇提取物浓度分别为10%、20%、40%和80%。之后,用卡尺测量圆盘周围的透明区域。单因素方差分析结果显示p=0.000 (p<0.05)。这意味着在整个治疗组中存在显著差异。Post Hoc LSD测试结果显示,样本组之间存在显著差异。因此,大蒜(Allium sativum L.)乙醇提取物作为溶剂在海藻酸盐印模材料中具有体外抑制白色念珠菌生长的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inhibition of Garlic Ethanol Extracts (Allium Sativum L.) as a Solvent in Alginate Impression Materials in the Growth of Candida Albicans
Alginate is an impression material currently used in dentistry because it has numerous advantages. However, alginate will come into direct contact with blood, saliva, and plaque in its use. Hence, it has the potential to contain pathogenic micro-organisms. One of the micro-organisms that can be pathogenic is Candida Albicans. It can infect the oral cavity and cause candidiasis. Therefore, it is necessary to inhibit Candida Albicans’ growth in the form of a natural ingredient from garlic (Allium sativum L.). Garlic (Allium sativum L.) has benefits as an antifungal since it has an active ingredient, namely allicin. The objective is examining the effect of garlic (Allium sativum L.) ethanol extract as a solvent in alginate impression materials on the growth inhibition of Candida Albicans. The research method was disc diffusion with alginate manipulation using a solvent in distilled water and with ethanol extract of garlic concentrations of 10%, 20%, 40%, and 80%. After that, the clear zone around the disc was measured with a caliper. One-way ANOVA test results indicated that the value was p=0.000 (p<0.05). It means that there were significant differences in the entire treatment group. The results of the Post Hoc LSD test showed that there were significant differences among the sample groups. Therefore, the ethanol extract of garlic (Allium sativum L.) as a solvent in the alginate impression material has an effect on the growth inhibition of Candida Albicans (in vitro).
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