在这里,以碳为基础的域决定了所有生物化学的可能排列

Rajasekaran Ekambaram
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引用次数: 9

摘要

蛋白质序列是埋藏在特定蛋白质内部的所有相关信息的主要来源。同时,在结构相似和序列不相似的蛋白质中持续保守的位置保留了蛋白质的折叠和功能,以有序/无序的方式进行调节进化支配着蛋白质功能的可获得的隐性信息所有可用的功能单元都是所有主导力的少数残基长度守恒改变这些残留物可能是亲水聚焦的观点,这种保守的主导引力存在被打破。所有中性残基对于维持蛋白质功能的最佳功能变化可能是至关重要的这些重要功能部分的亲水性可能一直是疾病的关键来源。疏水相互作用似乎对蛋白质之间的折叠和患病蛋白质很重要。慢运动对于与疏水相互作用有关的蛋白质功能环的重要性需要在这个时候讨论。来自元源的功能单元如果服务于所有时间源的元蛋白,则可能是危重疾病。根据所有单独序列信息的始终高可见交互媒体焦点的元源,重点介绍了患病序列。例如,酶在某种意义上更受关注,因为催化作用的化学反应一直是人们关注的焦点。从亲水聚焦的角度来看,在这个关键时刻需要对催化位点的全时间聚焦有一个理性的认识。序列是所有时间的水亲和聚焦的来源,从这个角度来看,必须从活性氨基酸沿着感兴趣的序列设计定量。很好,没有直接测量水感焦点的方法,但设计了间接测量水感焦点的方法。在整个测量过程中,最终的焦点是被测者从亲水角度所观察到的焦点。标定就是把焦点放在直接对焦点机构进行测量的测量装置上。例如,所有的序列都集中在测量单个氨基酸的结合能力,这是单个管理系统单独测量的焦点。例如,突变比直接测量所有时间集中的个体改变更集中在感兴趣的氨基酸上。模型是所有时间的结合能力的中心焦点单个雕刻的模型专注于单个感兴趣的氨基酸的结合这是这里研究的中心焦点一直以来都专注于单个感兴趣的氨基酸水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Domains based in carbon dictate here the possible arrangement of all chemistry for biology
Protein sequences are the primary sources of all related information buried inside a given protein. At the same time persistently conserved positions in structurally similar and sequence dissimilar proteins preserve protein fold and function2 adjusting both in order/disordered one.3 Evolution dominates the available buried information for function of protein.4 All available functional units are few residue lengths conserved of all dominant force.5 Changing these residues might be hydropathy focusing point of view that this conserved dominant force of attraction present is broken. All neutral residues are likely to be critically important for maintaining optimal functional variation of protein function of all time.6 Hydrophilic of these functionally important portions might be the critical sources of disease all time in. Hydrophobic interaction is seemingly important for protein to fold among themselves7 and in diseased proteins. The importance of slow motions for protein functional loops8 related to hydrophobic interaction is needed to be discussed at this hour. Functional unit coming from meta sources might be the critically diseased if it serve for meta protein of all time sources. According to meta sources of all time high visible interactive media focus of all alone sequence information, the emphasis is given for the diseased one. Enzyme for example is focused more in the sense that the chemistry of catalytic action being the focus point of all time. Given the situation hydropathy focusing point of view, a rational view point for catalytic site of all time focus is needed at this juncture. Sequence being the source of all time hydropathy focusing point of view, ration has to be devised for that point of view from active amino acid all along the sequence of interest. Good that there is no direct measure of hydropathy focusing point, but indirect one is devised for that. All along the measurement, focus is being given for end that is being focal point of view in the sense that views from the hydropathy point of view measured. Calibration is being focal point on that device of measure which is measured directly on mechanism of focus. Sequence for example, all focused on measurement of binding capability of individual amino acids that are focal point of view of the individual management system that are individually measured. Mutation for example focused more than that of direct measurement of all time focused individual alteration focused in amino acid of interest. Models are central focus of all time binding capabilities of individually carved one that is being focused on binding of individual amino acid of interest that is taken up here for study as central focal theme of interest of all time focused individually at amino acid level of interest of all time here.
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