Qingjie Wang, S. Kharche, Gareth M. Jones, Cunjin Luo, Chengchun Tang, Henggui Zhang
{"title":"钙漏致小鼠心房结和心室细胞心律失常的模拟研究。","authors":"Qingjie Wang, S. Kharche, Gareth M. Jones, Cunjin Luo, Chengchun Tang, Henggui Zhang","doi":"10.1109/EMBC.2015.7319391","DOIUrl":null,"url":null,"abstract":"Bradycardia is found to be a complication during catecholaminergic polymorphic ventricular tachycardia in which calcium leak plays a pivotal role. In this computational study, we determined the effects of sarcoplasmic reticulum calcium leak on the function of sino-atrial node and ventricular model cells.","PeriodicalId":72689,"journal":{"name":"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference","volume":"34 1","pages":"4487-90"},"PeriodicalIF":0.0000,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Calcium leak induced arrhythmias in mouse sino-atrial node and ventricle cells: A simulation study.\",\"authors\":\"Qingjie Wang, S. Kharche, Gareth M. Jones, Cunjin Luo, Chengchun Tang, Henggui Zhang\",\"doi\":\"10.1109/EMBC.2015.7319391\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bradycardia is found to be a complication during catecholaminergic polymorphic ventricular tachycardia in which calcium leak plays a pivotal role. In this computational study, we determined the effects of sarcoplasmic reticulum calcium leak on the function of sino-atrial node and ventricular model cells.\",\"PeriodicalId\":72689,\"journal\":{\"name\":\"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\",\"volume\":\"34 1\",\"pages\":\"4487-90\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/EMBC.2015.7319391\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/EMBC.2015.7319391","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Calcium leak induced arrhythmias in mouse sino-atrial node and ventricle cells: A simulation study.
Bradycardia is found to be a complication during catecholaminergic polymorphic ventricular tachycardia in which calcium leak plays a pivotal role. In this computational study, we determined the effects of sarcoplasmic reticulum calcium leak on the function of sino-atrial node and ventricular model cells.