年轻男性ALK阳性非小细胞肺癌患者大量血栓栓塞导致弥漫性脑梗死:ALK重排与血栓形成有关吗?

Z. Urakçı, Sezai Tunç, F. Keskin, Hayati Arvas, Z. Oruç, A. Işıkdoğan
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引用次数: 0

摘要

肺腺癌患者发生血栓栓塞的风险很高,尤其是ALK重排患者。ALK重排导致血栓形成的机制尚不清楚。在此,我们报告一位25岁的年轻男性患者,同时患有肺腺癌和ALK重排,并因大量血栓栓塞而导致弥漫性脑梗死。当ALK重排肺癌患者出现颅内症状时,除了转移外,还应注意血栓形成。此外,这些患者在诊断和治疗过程中都应密切关注血栓形成情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diffuse Cerebral Infarction Due to Massive Thromboembolism in A Young Male Patient With ALK-Positive Non-Small Cell Lung Cancer: Is the ALK Rearrangement Related to Thrombosis?
The risk of thromboembolism is high in patients with lung adenocarcinoma, especially in patients with ALK rearrangement. The mechanism of thromboembolism due to ALK rearrangement is still unknown. Here, we present a case of diffuse cerebral infarction due to massive thromboembolism in a 25-year-old young male patient with lung adenocarcinoma and ALK rearrangement. Thrombosis, apart from metastasis, should be kept in mind when cranial symptoms develop in patients with lung cancer with ALK rearrangement. In addition, these patients should be followed closely in terms of thrombosis both at diagnosis and during treatment.
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