连续流左心室辅助装置后华法林时间在治疗范围内的预测因素

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2019-10-01 DOI:10.1002/phar.2324

James B. Henderson, P. Iyer, A. C. Coniglio, J. Katz, C. Chien, I. Hollis

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引用次数: 12

摘要

使用连续血流左心室辅助装置(CF‐LVAD)的患者需要使用维生素K拮抗剂抗凝以预防血栓栓塞事件。国际标准化比值的波动与血栓和出血发作的增加有关。迄今为止，CF‐LVAD患者的低治疗时间范围(TTR)的危险因素尚未被探讨。

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Predictors of Warfarin Time in Therapeutic Range after Continuous‐Flow Left Ventricular Assist Device

Patients with a continuous‐flow left ventricular assist device (CF‐LVAD) require anticoagulation with a vitamin K antagonist to prevent thromboembolic events. Fluctuations in the international normalized ratio are associated with both increased thrombotic and bleeding episodes. To date, risk factors for low time in therapeutic range (TTR) among ambulatory patients with a CF‐LVAD have not been explored.

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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

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