不同氟化物对仓鼠实验性根面龋发育的影响。

D. Jg
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引用次数: 3

摘要

本研究的目的是评价局部应用不同氟化物对仓鼠牙根表面龋形成的影响。将115只雄性金仓鼠分为7组,给予促龋饮食。6组感染粘胶放线菌ATCC 15987;对5个感染组,采用蒸馏水(DW)和含有500 ppmF酸化磷酸氟(APF)、氟化亚锡(SnF2)、氟化铜(CuF2)和四氟化钛(TiF4)的溶液,每天1次,每周7天,连续24周局部涂于第一下颌磨牙。采用网格法对第一磨牙牙周变化及根面龋病进行评估。SnF2减少斑块堆积最多;SnF2和CuF2对牙槽骨丢失的抑制作用更大。与感染对照组相比,所有氟化物组均可显著预防根表面龋病;TiF4是最有效的氟化合物,其次是SnF2、CuF2和APF。TiF4和SnF2组的根龋评分显著低于DW组。结果表明,所测氟化物均可预防仓鼠牙根表面龋病的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of various fluoride compounds on the development of experimental root surface caries in hamsters.
The aim of this investigation was to evaluate the effect of topical applications of various fluoride compounds on the development of root surface caries in hamsters. Male golden hamsters (n = 115) were divided into 7 groups and were given a caries-promoting diet. Six groups were infected with Actinomyces viscosus ATCC 15987; and to 5 infected groups, distilled water (DW) and solutions containing 500 ppmF of acidulated-phosphate fluoride (APF), stannous fluoride (SnF2), copper fluoride (CuF2), and titanium tetrafluoride (TiF4) were applied topically to the first mandibular molars once daily, 7 days a week, over a 24-week period. A grid method was used to asses the periodontal changes and root surface caries on the first molars. Plaque accumulation was reduced most by SnF2; and alveolar bone loss was more reduced by SnF2 and CuF2. Root surface caries was significantly prevented in all fluoride groups when compared to an infected control group; and TiF4 was the most effective fluoride compound followed by SnF2, CuF2, and APF. Root caries scores of the TiF4 and SnF2 groups were significantly lower than those of the DW group. It was concluded that all fluoride tested may prevent the development of root surface caries in hamsters.
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