{"title":"急性缺血性脑卒中的超声溶栓治疗:目前的证据和新的进展","authors":"Jürgen Eggers","doi":"10.1016/j.permed.2012.02.022","DOIUrl":null,"url":null,"abstract":"<div><p>Sonothrombolysis is a novel therapy for recanalization of acute intracranial arterial occlusion. So far, safety and efficacy has been shown for transcranial ultrasound with diagnostic probes in combination with standard thrombolysis treatment. However, there are several new developments including special designed ultrasound probes, microspheres for enhancement of the thrombolytic effect of ultrasound and other new approaches. This review provides an overview of current evidence from randomized controlled trials and perspectives on this topic.</p></div>","PeriodicalId":101010,"journal":{"name":"Perspectives in Medicine","volume":"1 1","pages":"Pages 14-20"},"PeriodicalIF":0.0000,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.022","citationCount":"8","resultStr":"{\"title\":\"Sonothrombolysis for treatment of acute ischemic stroke: Current evidence and new developments\",\"authors\":\"Jürgen Eggers\",\"doi\":\"10.1016/j.permed.2012.02.022\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Sonothrombolysis is a novel therapy for recanalization of acute intracranial arterial occlusion. So far, safety and efficacy has been shown for transcranial ultrasound with diagnostic probes in combination with standard thrombolysis treatment. However, there are several new developments including special designed ultrasound probes, microspheres for enhancement of the thrombolytic effect of ultrasound and other new approaches. This review provides an overview of current evidence from randomized controlled trials and perspectives on this topic.</p></div>\",\"PeriodicalId\":101010,\"journal\":{\"name\":\"Perspectives in Medicine\",\"volume\":\"1 1\",\"pages\":\"Pages 14-20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.permed.2012.02.022\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Perspectives in Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211968X12000290\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Perspectives in Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211968X12000290","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sonothrombolysis for treatment of acute ischemic stroke: Current evidence and new developments
Sonothrombolysis is a novel therapy for recanalization of acute intracranial arterial occlusion. So far, safety and efficacy has been shown for transcranial ultrasound with diagnostic probes in combination with standard thrombolysis treatment. However, there are several new developments including special designed ultrasound probes, microspheres for enhancement of the thrombolytic effect of ultrasound and other new approaches. This review provides an overview of current evidence from randomized controlled trials and perspectives on this topic.