维生素D受体在前驱糖尿病中的作用

S. Kharb, K. Goel, R. Rajput
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引用次数: 0

摘要

最近的流行病学证据表明,维生素D不足与不良代谢风险以及癌症、心血管疾病、2型糖尿病和其他疾病的发病机制存在潜在关联。维生素D通过维生素D受体在多种细胞类型中发挥作用。文献中没有关于前驱糖尿病患者维生素D和维生素D受体状态的报道。本研究旨在比较糖尿病前期患者和正常血糖对照者血清25-羟基维生素D [25(OH)D]和维生素D受体(VDR)蛋白水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Vitamin D Receptor in Prediabetes
Recent epidemiological evidence points towards the potential association of vitamin D insufficiency with adverse metabolic risk and in the pathogenesis of cancer, cardiovascular diseases, type 2 diabetes and other diseases. Vitamin D exerts its action in a variety of cell types through vitamin D receptors. No reports are available in the literature regarding vitamin D and vitamin D receptor status in prediabetics. The present study was planned to compare serum 25-hydroxy vitamin D [25(OH)D] and vitamin D receptor (VDR) protein levels in prediabetic cases and normoglycemic controls.
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