仿生抗菌传感丝生物贴片

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI:10.1109/Transducers50396.2021.9495518

Zhiheng Gao, T. Tao, Keyin Liu

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引用次数: 0

摘要

我们报道了一类具有细菌抑制和感染监测功能的仿生丝基生物贴片。丝质生物贴片的力学性能可以很好地调整到与人体贴片(如硬脑膜和疝贴片)的弹性模量相匹配。该生物贴片可以通过添加生物活性药物和生物因子来实现功能化。利用光学衍射元件(DOE)在丝绸生物贴片上的微图案可以实现细菌抑制。此外，生物贴片中的DOE可以通过检测衍射模式的变化来监测组织感染。我们的方法为开发生物医学应用的多功能植入式装置提供了潜力。

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Biomimic Antibacterial Sensing Silk Bio-Patch

We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.

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来源期刊

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)

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