紫外分光光度法测定酸性和碱性介质对非索非那定品牌的影响

Canadian journal of applied sport sciences. Journal canadien des sciences appliquees au sport Pub Date : 2015-01-01 DOI:10.21065/19257430.5.1

S. Naveed

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引用次数: 4

摘要

非索非那定是一种选择性组胺H1受体拮抗剂，被广泛用于过敏性疾病，特别是Rhiniti。在我们最近的研究中，我们研究了酸性和碱性介质对四种不同品牌非索非那定的影响，为此，我们将不同品牌非索非那定的溶液分别进行了中性、碱性和酸性介质的处理。当非索非那定品牌在0.1N HCl和0.1N NaOH作用30分钟时，非索非那定品牌的有效性结果是可变的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EFFECT OF ACIDIC AND ALKALINE MEDIUM ON FEXOFENADINE BRANDS USING UV SPECTROPHOTOMETER

Fexofenadine is widely used drug for allergic conditions especially Rhiniti and is a selective histamine H1 receptor antagonist. In our recent research we study the effect of acidic and alkaline medium on four different brands of Fexofenadine, for this the solutions of different brands of Fexofenadine were subjected to neutral,alkaline and acidic medium. When Fexofenadine brands subjected to 0.1 N HCl and 0.1N NaOH for 30 minutes, Fexofenadine brands showed variable availability results.

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Canadian journal of applied sport sciences. Journal canadien des sciences appliquees au sport

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