一系列功能化芳基苯并噻唑的结构-抗菌活性关系

Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition Pub Date : 2019-01-13 DOI:10.3390/MOL2NET-04-06133

A. Fatma, M. E. Arbi, M. S. Veitía, Mamdouh Ben Ali, C. Ferroud

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引用次数: 0

摘要

研究了一系列功能性芳苯并噻唑对革兰氏阳性病原菌包括金黄色葡萄球菌(ATCC 9144)、黄体微球菌(LB14110)、肠炎沙门氏菌(NCTC 6017)和革兰氏阴性食源性铜绿假单胞菌(ATCC 9027)、大肠杆菌(ATCC 8739)的抑菌活性。对条件致病性白色念珠菌(ATCC 2091)的抗真菌活性也进行了评估。结果表明，与夫西地酸相比，这些化合物具有良好的抑菌活性。并讨论了结构与抗菌活性的关系

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Structure-antimicrobial activity relationship of a series of functionalized arylbenzothiazoles

The antibacterial activity of a series of functionalized arybenzothiazoles was investigated against Gram-positive pathogens including Staphylococcus aureus (ATCC 9144), Micrococcus luteus (LB14110), Salmonella enterica (NCTC 6017) and Gram-negative foodborne Pseudomonas aeruginosa (ATCC 9027), Escherichia coli (ATCC 8739). The antifungal activity was also evaluated against the opportunistic pathogenic yeast Candida albicans (ATCC 2091). The results displayed that these compounds exhibit a good antimicrobial activity compared with fusidic acid. The structure-antimicrobial activity relationships are also discussed

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Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition

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