胡椒碱-4- 1及其衍生物的合成与结晶研究进展

IF 1.4 3区管理学 Q2 INFORMATION SCIENCE & LIBRARY SCIENCE

College & Research Libraries Pub Date : 2021-06-17 DOI:10.22034/CRL.2021.278234.1105

Arulraj Ramalingam

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引用次数: 1

摘要

哌啶是由吡啶氢化形成的杂环化学分子。在天然药物和具有药理活性的药物中，哌啶环是必不可少的分子成分。报道了哌啶-4- 1及其衍生物的几种晶体结构及其药用价值。虽然已经开发了几种胡椒碱-4- 1结晶方法来获得晶体结构，但仍然需要新的方法。本文综述了胡椒碱-4- 1及其衍生物的合成和结晶过程。

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Synthesis and crystallization procedure of piperidin-4-one and its derivatives: An update

Piperidine is a heterocyclic chemical molecule that is forming by hydrogenating pyridine. In natural and pharmaceutically active drugs, the piperidine ring is an essential molecular component. Several crystal structures of piperidine-4-ones and their derivatives are reported for their medicinal value. While several methods of piperidin-4-one crystallization have been developed to obtain a crystal structure, novel approaches are still needed. A review of the synthesis and crystallization procedure of piperidin-4-ones and its derivatives is outlined in this review paper.

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来源期刊

College & Research Libraries INFORMATION SCIENCE & LIBRARY SCIENCE-

CiteScore

3.10

自引率

22.20%

发文量

审稿时长

45 weeks

期刊介绍： College & Research Libraries (C&RL) is the official scholarly research journal of the Association of College & Research Libraries, a division of the American Library Association, 50 East Huron St., Chicago, IL 60611. C&RL is a bimonthly, online-only publication highlighting a new C&RL study with a free, live, expert panel comprised of the study''s authors and additional subject experts.