儿童嗜酸性胃炎。如何怀疑?诊断标准

I. Berezhnaya, L. Goncharova, I. D. Maikova, E. R. Radchenko, E. I. Epifanova, E. Skorobogatova, I. Osmanov, I. Zakharova, A. S. Koshurnikova
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摘要

本综述的目的:通过对一个临床病例的分析,分析目前有关儿童胃嗜酸性粒细胞病变的资料。要点。与原发性组织嗜酸性粒细胞增多相关的胃肠道疾病是以炎症为特征的异质性变化,在没有其他已知原因的情况下,主要是嗜酸性粒细胞组织浸润。胃肠道变应性炎症性疾病的临床表现通常是非特异性的。根据病变程度,嗜酸性粒细胞可分为胃炎、肠炎和结肠炎。近年来,越来越多的专家关注这一领域的研究,但到目前为止,没有关于成人和儿童在人群中患病率的一般流行病学数据。结论。目前,儿童胃、小肠和大肠嗜酸性粒细胞病变的诊断尚无明确的形态学标准,临床表现,特别是幼儿的临床表现也不具有特异性。在诊断EoG时,有必要考虑家族过敏史,一组实验室诊断数据(临床血液检查嗜酸性粒细胞增多和高水平的总IgE)和胃粘膜活检的形态学研究。关键词:儿童,嗜酸性胃炎,嗜酸性粒细胞增多,组织嗜酸性粒细胞增多,食物过敏。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Eosinophilic Gastritis in a Child. How to Suspect? Diagnostic Criteria
Objective of the Review: To analyze current data on eosinophilic lesions of the stomach in children with the analysis of a clinical case. Key points. Diseases of the gastrointestinal tract associated with primary tissue eosinophilia are a heterogeneous group of changes characterized by inflammation, with predominantly eosinophilic tissue infiltration in the absence of other known causes. Clinical manifestations of allergic inflammatory diseases of the gastrointestinal tract are most often nonspecific. Depending on the level of the lesion, eosinophils are distinguished: gastritis (EoG), enteritis, and colitis. In recent years, more and more attention of experts has been directed to research in this area, but so far there are no general epidemiological data on the prevalence of this pathology in the population, both adults and children. Conclusion. Currently, there are no clear morphological criteria for diagnosing eosinophilic lesions of the stomach, small and large intestine in children, and clinical manifestations, especially in young children, are nonspecific. When making a diagnosis of EoG, it is necessary to take into account a family allergic history, a set of laboratory diagnostic data (eosinophilia in a clinical blood test and a high level of total IgE) and a morphological study of a biopsy of the gastric mucosa. Keywords: children, eosinophilic gastritis, eosinophilia, tissue eosinophilia, food allergy.
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