{"title":"PET-CT监测在胰腺癌治疗中的应用","authors":"G. Roitberg, O. Anikeeva","doi":"10.37748/2687-0533-2020-1-4-7","DOIUrl":null,"url":null,"abstract":"Pancreatic cancer is a disease characterized by low visualization, high metastasis, and lethality. The average life expectancy for this nosology is less than 1 year. Early diagnosis of pancreatic cancer is difficult due to the lack of specific symptoms. As a rule, at the time of tumor visualization, every third patient has regional lymph nodes involved in the process, and every second patient already has distant metastases. We present a clinical case of a 73-year-old patient with a diagnosis of: cancer of the pancreatic head St IV, T4N1M1. The woman's primary positron emission tomography (PET-CT) revealed a metabolically active lesion with a size of 26х21х32 mm. After the combined multi-stage therapy under the control of PET-CT, it was possible to achieve complete leveling of the primary tumor focus and a relapse-free course of the disease for 11 months. Our clinical observation showed the effectiveness of dynamic control (using PET-CT) treatment of metastatic pancreatic cancer, which influenced the patient's treatment strategy. Conclusion . Patients with pancreatic adenocarcinoma ECOG ≥ 3, despite the prevalence of the process, should be offered comprehensive treatment.","PeriodicalId":22147,"journal":{"name":"South Russian Journal of Cancer","volume":"12 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PET-CT monitoring in the treatment of pancreatic cancer\",\"authors\":\"G. Roitberg, O. Anikeeva\",\"doi\":\"10.37748/2687-0533-2020-1-4-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pancreatic cancer is a disease characterized by low visualization, high metastasis, and lethality. The average life expectancy for this nosology is less than 1 year. Early diagnosis of pancreatic cancer is difficult due to the lack of specific symptoms. As a rule, at the time of tumor visualization, every third patient has regional lymph nodes involved in the process, and every second patient already has distant metastases. We present a clinical case of a 73-year-old patient with a diagnosis of: cancer of the pancreatic head St IV, T4N1M1. The woman's primary positron emission tomography (PET-CT) revealed a metabolically active lesion with a size of 26х21х32 mm. After the combined multi-stage therapy under the control of PET-CT, it was possible to achieve complete leveling of the primary tumor focus and a relapse-free course of the disease for 11 months. Our clinical observation showed the effectiveness of dynamic control (using PET-CT) treatment of metastatic pancreatic cancer, which influenced the patient's treatment strategy. Conclusion . Patients with pancreatic adenocarcinoma ECOG ≥ 3, despite the prevalence of the process, should be offered comprehensive treatment.\",\"PeriodicalId\":22147,\"journal\":{\"name\":\"South Russian Journal of Cancer\",\"volume\":\"12 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-11-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"South Russian Journal of Cancer\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37748/2687-0533-2020-1-4-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"South Russian Journal of Cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37748/2687-0533-2020-1-4-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
胰腺癌是一种低显像、高转移、高致死率的疾病。这种疾病的平均预期寿命不到1年。由于缺乏特异性症状,胰腺癌的早期诊断很困难。通常,在肿瘤显像时,每三名患者中就有一名涉及到局部淋巴结,每两名患者中就有一名已经有远处转移。我们提出了一个73岁的临床病例患者的诊断:胰腺癌的头St IV, T4N1M1。该妇女的初级正电子发射断层扫描(PET-CT)显示一个代谢活性病变,大小为26х21х32 mm。在PET-CT的控制下,经多期联合治疗,原发病灶完全平整,11个月无复发。我们的临床观察显示动态控制(使用PET-CT)治疗转移性胰腺癌的有效性,影响患者的治疗策略。结论。胰腺腺癌ECOG≥3的患者,尽管该过程普遍存在,但仍应给予综合治疗。
PET-CT monitoring in the treatment of pancreatic cancer
Pancreatic cancer is a disease characterized by low visualization, high metastasis, and lethality. The average life expectancy for this nosology is less than 1 year. Early diagnosis of pancreatic cancer is difficult due to the lack of specific symptoms. As a rule, at the time of tumor visualization, every third patient has regional lymph nodes involved in the process, and every second patient already has distant metastases. We present a clinical case of a 73-year-old patient with a diagnosis of: cancer of the pancreatic head St IV, T4N1M1. The woman's primary positron emission tomography (PET-CT) revealed a metabolically active lesion with a size of 26х21х32 mm. After the combined multi-stage therapy under the control of PET-CT, it was possible to achieve complete leveling of the primary tumor focus and a relapse-free course of the disease for 11 months. Our clinical observation showed the effectiveness of dynamic control (using PET-CT) treatment of metastatic pancreatic cancer, which influenced the patient's treatment strategy. Conclusion . Patients with pancreatic adenocarcinoma ECOG ≥ 3, despite the prevalence of the process, should be offered comprehensive treatment.