nnumg果皮的胶囊壳配方(Artocarpus hepelalus Lam)和胶囊碎时间试验

Rosiana Rizal, Salman Salman, E. Wulandari
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引用次数: 0

摘要

胶囊是由药物组成的软胶囊和硬胶囊出售的胶囊制剂。胶囊是大多数人用来发现药物令人不快的味道的制剂。大多数出售的胶囊是由明胶制成的,但也可以用淀粉或其他成分制成。另一种可以代替明胶的成分是果胶。果胶是一种属于碳水化合物类的成分。本研究旨在寻找其他可作为胶囊销售新成分的替代品,即杰克果皮。将杰克果皮20毫克溶于1000毫升蒸馏水中,加入5%柠檬酸。然后在热板上提取,搅拌速度600 rpm,温度85ºC, 120分钟。所得收率为0.319%。最佳配方为2 (0.7 g果胶、5.00 g卡拉胶、100ml蒸馏水)。评价结果为胶囊销售标准中药体直径为6.2 mm、6.3 mm、药盖直径、药体长度为15.2 mm、药盖长度为07.8 mm,不合格药囊重量为0.09 g。嗅觉结果为浅棕色,质地稍响,无香味。胶囊销售崩解应符合印尼药典第五版规定的要求,为13分47秒。关键词:菠萝蜜皮,果胶,囊壳
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FORMULASI CANGKANG KAPSUL DARI PEKTIN KULIT BUAH NANGKA (Artocarpus heterophyllus Lam) DAN UJI WAKTU HANCUR KAPSUL
Capsule is capsule preparations which consisting of a drug in a soft capsule and hard capsule sell. Capsule is the preparations that most people used to discover the unpleasant taste of the drug. Most of capsule sell are made of gelatin, but it can also made with starch or other ingredients. The other ingredients which can substitute gelatin is pectin. Pectin is an ingredient belong to the class of carbohydrates. This study aim to find others alternative that can be used as new ingredients of capsule sell, which is jack fruit peels. Dissolved 20 mg jack fruit peels in 1000 ml of distilled water and, added 5% of citric acid. Then extracted on a hot plate with a stirring speed 600 rpm, temperature of 85ͦC, for 120 minutes. The yield obtained was 0.319%. The best formulations results were 2 (0.7 gram pectin, 5.00 gram carrageenan, 100ml disttiled water). The result of the evaluation of capsule sell standards with a body diameter of 6,2 mm, 6,3 mm, of a lid diameter, a body length of 15,2 mm, a lid length of 07.8 mm, and those that are unqualified with 0.09 gram of capsule weights. The organleptic results are light brown color, texture a little loud and there is no fragrance. The capsule sell disintegration should meet the requirements set by the Indonesian Pharmacopoeia V edition, is 13 minutes 47 seconds.Keywords: jackfruit skin (Artocarpus heterophyllus Lam), pectin, capsule shell
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