自身免疫性癫痫的诊断和治疗相关问题

Q4 Medicine

Epilepsy and Paroxysmal Conditions Pub Date : 2023-07-09 DOI:10.17749/2077-8333/epi.par.con.2023.130

O. Shilkina, E. E. Timechko, D. Dmitrenko

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引用次数: 0

摘要

由于自身免疫性癫痫病例的频率升高，与建立疾病病因的可靠临床和实验室仪器标准相关的问题变得相关。自身抗体标记物的差异化评估允许选择最有效的策略来管理患者。本文介绍了评估自身免疫性癫痫的标准，以及基于合成自身抗体类型的诊断量表、与临床表现相关的特征和对治疗的反应。本文详细介绍了用于自身免疫性癫痫的免疫调节和抗癫痫药物的治疗线和靶点，这些知识以及临床和实验室数据共同允许确定有效和安全的治疗算法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diagnosis and treatment-related issues of autoimmune epilepsy

Due to elevated frequency of autoimmune epilepsy cases, the issues related to reliable clinical and laboratory-instrumental criteria for establishing the disease etiology become relevant. Differentiated assessment of autoantibody markers allows to choose the most effective tactics for managing patients. The article presents the criteria for assessing autoimmune epilepsy as well as diagnostic scales, features related to clinical picture and response to therapy based on the type of synthesized autoantibodies. Therapeutic lines and targets for immunomodulatory and antiepileptic drugs used in autoimmune epilepsy are detailed, the knowledge of which along with clinical and laboratory data collectively allow to determine effective and safe therapy algorithm.

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来源期刊

Epilepsy and Paroxysmal Conditions Medicine-Neurology (clinical)

CiteScore

0.90

自引率

0.00%

发文量

审稿时长

8 weeks