新型环己酮苯甲酰腙的合成、表征及抑菌抑菌评价

Gökçe Cihan-Üstündağ, Emel Mataracı-Kara, G. Çapan
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引用次数: 2

摘要

合成并评价了一系列新型苯甲酰腙(2a-j)在体外对选定细菌和真菌的抗菌活性。通过IR、1H-NMR、13C-NMR (APT)、电喷雾质谱(ESI-MS)和微量分析(C、H、N)对化合物结构进行了表征。除化合物2h外,其余化合物对表皮葡萄球菌ATCC 12228和金黄色葡萄球菌ATCC 29213均表现出较弱的抑菌活性。化合物2a、2b、2e、2f和2i对假丝酵母菌有一定的抗真菌活性。你可以将这篇文章引用为:Cihan-Ustundag G, Mataraci-Kara E, Capan G(2019)。新型环己酮苯甲酰腙的合成、表征及抑菌抑菌评价IstanbulJPharm 10.26650/ istanbuljpharma .2019.19022。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis, Characterization, Antibacterial and Antifungal Evaluation of Novel Cyclohexanone Benzoylhydrazones
DOI : 10.26650/IstanbulJPharm.2019.19022 A novel series of benzoyl hydrazones (2a-j) have been synthesized and evaluated, in vitro, for antimicrobial activity against selected bacteria and fungi. The structures of the compounds were established by IR, 1H-NMR, 13C-NMR (APT), electrospray ionization mass spectrometry (ESI-MS) and microanalysis (C, H, N). All of the tested compounds, except for compound 2h, displayed weak antibacterial properties against Staphylococcus epidermidis ATCC 12228 and Staphylococcus aureus ATCC 29213. Compounds 2a, 2b, 2e, 2f and 2i further exhibited marginal antifungal activity against Candida parapsilosis. You may cite this article as : Cihan-Ustundag G, Mataraci-Kara E, Capan G (2019). Synthesis, Characterization, Antibacterial and Antifungal Evaluation of Novel Cyclohexanone Benzoylhydrazones. Istanbul J Pharm 10.26650/IstanbulJPharm.2019.19022.
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