FORECASTING OF TRIAZOLE, AMIDE, PIPEREDINYLE THIAZOL ISOXAZOLINE, OXAZOLE FUNGICIDES HAZARDOUS EFFECT ON HUMAN HEALTH IN CONSUMPTION OF VEGETABLES GROWED IN THEIR APPLICATION

The chemical plant protection products application is an integral part of intensive crop production technologies. However, scientists have proven that the increase in chemical pollution of the environment in 2 times increases the general level of morbidity of the adult population by 25%. That is why the risk assessment of pesticide-contaminated products consumption is an important part of the regulatory process. Methods. The parameters of fungicides difenoconazole, tebuconazole, cyflufenamid, oxathiapiprolin, famoxadone persistence in agricultural crops were studied in the field experiments. For the integrated assessment of the potential risk of pesticide-contaminated products consumption for human (RPCPC), a methodology developed on the basis of the Institute of Hygiene and Ecology was used. The acceptable daily intake (ADI), the half-life period (τ50) in plants and the average daily consumption of the product have been evaluated using four-graded scale. Results. According to the persistency in tomatoes and potatoes, fungicides difenoconazole, cyflufenamid, famoxadone are pertained to 3 classes of hazard (5-14 days); tebuconazole - to 2 class (15-30 days); oxathiapiprolin - to 4 class (less than 5 days). After the addition of all the obtained points, the RPCPC value (tomatoes and potatoes) for difenoconazole, cyflufenamid, famoxadone amounted 8 points (2+2+2× 2 and 2+2+4, respectively); tebuconazole - 8 points (3+1+2×2 or 3+1+4, respectively); oxathiapiprolin - 6 points (1+1+2×2 or 1+1+4, respectively). Discussion. Thus, the studied compounds belong to the 3rd class of hazard according to pesticide-contaminated products consumption for human index value. The results obtained by us correlate with the studies carried out in the previous stage. The exception was only difenoconazole, which was classified as hazard class 2 due to its high toxicity for human.