弓形虫病和交叉反应:免疫印迹分析血清学反应

J. Dave, D.S. Tompkins, R.P. Eglin, J.P. Harford
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引用次数: 1

摘要

在没有其他弓形虫感染证据的患者中可发现与弓形虫抗原(天然抗体)发生反应的抗体。采用免疫印迹法(Western blotting)检测37份染色试验(DT)阴性血清的天然抗体谱。这37份血清中有11份间接血凝试验弓形虫抗体阳性,8份类风湿因子阳性,18份来自急性病毒感染患者。这三组血清不能通过Western blot反应相互区分,也不能从未感染弓形虫的患者的血清中区分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Toxoplasmosis and cross-reactivity: an analysis of the serological response by immunoblotting

Antibodies which react with toxoplasma antigens (natural antibodies) can be found in patients without other evidence of toxoplasma infection. The natural antibody profile of 37 sera which were Dye Test (DT) negative was investigated by Western blotting with toxoplasma antigens. These 37 sera comprised 11 which were indirect haemagglutination test positive for toxoplasma antibodies, 8 rheumatoid factor positive and 18 from patients with acute viral infections. These three groups of sera could not be distinguished from each other, or from pooled sera from patients not infected with toxoplasma, by characterising the Western blot reactions.

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