抑郁是2型糖尿病发病的独立危险因素吗?

H. Parihar, Harivansh Thakar, H. Yin, Shari N. Allen
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引用次数: 3

摘要

抑郁症是最常见的精神疾病之一,其特征是失去快乐,而糖尿病是一种导致高血糖水平的代谢紊乱。目前的文献支持慢性疾病包括糖尿病患者抑郁症状的发展。然而,抑郁症作为糖尿病的潜在危险因素引起了临床医生和研究人员的广泛关注。据推测,糖尿病和抑郁症在本质上可能是双向的,每一方都可能加剧症状或在另一方的发展中发挥重要作用。它们之间最常见的联系是1型或2型糖尿病中抑郁症的诊断。事实上,据报道,糖尿病会使患抑郁症的风险增加一倍。在这篇综述文章中,我们总结了各种科学研究来评估抑郁症作为糖尿病危险因素的潜力。MEDLINE搜索发现了许多评估这一假设的文章。我们对文献的回顾表明,抑郁症是2型糖尿病的一个危险因素,但需要进行更多的临床研究来阐明抑郁症作为糖尿病的一个独立危险因素的作用,并防止糖尿病的流行以更高的速度升级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is depression an independent risk factor for the onset of Type 2 diabetes mellitus?
Depression is one of the most common mental illnesses characterized by loss of pleasure, whereas diabetes is a metabolic disorder which leads to high serum glucose levels. Current literature supports the development of depressive symptoms in patients with chronic illnesses including diabetes. However, depression as a potential risk factor for diabetes has attracted a lot of attention for clinicians and researchers. It has been hypothesized that both diabetes and depression may be bidirectional in nature, and each may exacerbate the symptoms or play an important role in the development of the other. The most common association between them is the diagnosis of depression in Type 1 or Type 2 diabetes. As the matter of fact, diabetes has been reported to double the risk of depression. In this review article, we have summarized various scientific studies to evaluate the potential of depression as a risk factor for diabetes. MEDLINE search identified various articles assessing this hypothesis. Our review of literature indicate some support for depression as a risk factor for Type 2 diabetes however more clinical studies need to be performed to clarify the contribution of depression as an independent risk factor for diabetes and to check the diabetes epidemic from escalating at a higher rate.
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