非黏液性腺癌:一个具有欺骗性表现的独特病例

Jason Pannozzo, S. Vyas, G. Letterio, Harold A Matos-Casano, U. Bhatt, W. Cruz-Vetrano
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引用次数: 0

摘要

以肺为表现的非黏液性肺腺癌是一种罕见的肺癌。它在患者表现和诊断成像方面模仿感染性和炎症性疾病的能力可能导致诊断延迟。本病例是在对一名60岁的非吸烟女性进行检查后发现的,她20年前从厄瓜多尔移民过来,过去两年在一家海岸维修店工作,她出现呼吸急促加重,体重在两个月内减轻了15磅。该患者表现的一个独特方面是,通常用来区分这种类型的肺腺癌与其他疾病过程的典型影像学和支气管镜检查结果缺失。CT检查未见结节性肿块,支气管镜检查未见病变或气道异常。直到活检和支气管肺泡灌洗(BAL)才确认腺癌的诊断。我们的病例旨在提高临床医生对不可预测的非粘液性卵泡腺癌的认识。此外,我们想强调在鉴别诊断中包括肺腺癌的相关性,即使感染性或职业性病因出现的可能性更大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-mucinous adenocarcinoma: a unique case with a deceptive presentation
Non-mucinous lepidic adenocarcinoma with pneumonic presentation is a rare form of lung cancer. Its ability to mimic infectious and inflammatory diseases in both patient presentation and diagnostic imaging can result in a delayed diagnosis. This case follows the workup of a 60-year-old non-smoker female who immigrated from Ecuador twenty years prior and worked at a shore repair shop for the past two years who presented with worsening shortness of breath and 15lbs weight loss over a two-month period. A unique aspect of this patient’s presentation was that the typical imaging and bronchoscopy findings often seen to distinguish this type of lung adenocarcinoma from other disease processes were absent. No nodular masses were observed on Computed Tomography (CT), and no lesions or airway abnormalities were seen on bronchoscopy. It was not until biopsy and bronchoalveolar lavage (BAL) that the diagnosis of adenocarcinoma was recognized. Our case aims to increase awareness among clinicians of the unpredictable presentation of nonmucinous lepidic adenocarcinoma. Furthermore, we want to highlight the relevance of including adenocarcinoma of the lung in the differential diagnosis even when infectious or occupational etiologies appear more likely.
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