南印度三级保健中心下肢和足部湿疹患者的临床人口学和斑贴试验概况

Ann Nisha, Navakumar Manickam, Kannan Gopalan, S. Vellaisamy
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摘要

背景:小腿和足部湿疹可能是由于外源性原因,如过敏性接触性皮炎(ACD)或内源性原因,如特应性。目前,斑贴试验是接触性过敏的唯一科学证据。目的:目的是研究临床人口学概况,并评估贴片试验在下肢和足部湿疹中的作用。材料和方法:这是一项横断面研究,在60例下肢和足部湿疹患者中进行。他们接受了印度标准系列的斑贴测试,读数根据国际接触性皮炎研究小组评分系统进行解释。结果:纳入男性32例(53.3%),女性28例(46.7%)(M: F = 1.1:1)。职业活跃年龄组平均年龄为42.61±13.40岁。男性中最常见的职业是建筑工人(10名[31.25%])(P = 0.007)。女性中最常见的是家庭主妇(10例[35.71%])(P = 0.0002)。最常见的湿疹类型为ACD(22例[36.7%])。17例(28.3%)患者出现斑贴试验阳性反应,最常见的过敏原为重铬酸钾(6例[35.3%])。将形态学与斑贴试验结果相比较,ACD(13例[59.1%])与其他湿疹(4例[10.53%])相比显著阳性(P = 0.000)。结论:斑贴试验是诊断下肢及足部湿疹的有效方法。它在识别与ACD相关的致病性过敏原方面起着关键作用,可以建议避免过敏原,以获得更好的临床结果和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinicodemographic and patch testing profile of patients with lower leg and feet eczema at a tertiary care center in South India
BACKGROUND: Lower legs and feet eczema may be due to exogenous causes such as allergic contact dermatitis (ACD) or endogenous cause such as atopy. Currently, patch testing is the only scientific proof of contact allergy. AIMS: The aim was to study the clinicodemographic profile and to evaluate the role of patch testing in lower leg and feet eczema. MATERIALS AND METHODS: This was a cross-sectional study conducted among 60 patients with lower leg and feet eczema. They were subjected to patch testing with Indian standard series and readings were interpreted according to the International Contact Dermatitis Research Group scoring system. RESULTS: Our study included 32 (53.3%) males and 28 (46.7%) females (M: F = 1.1:1). The mean age was 42.61 ± 13.40 years corresponding to occupationally active age group. Construction workers (10 [31.25%]) were the most common occupational group affected among males (P = 0.007). Among females, most commonly affected were housewives (10 [35.71%]) (P = 0.0002). The most common pattern of eczema seen was ACD (22 [36.7%]). Positive patch test response was recorded in 17 (28.3%) patients and the most common allergen found to be positive was potassium dichromate (6 [35.3%]). Correlating the morphology with patch test results, ACD (13 [59.1%]) was significantly positive when compared to other eczemas (4 [10.53%]) (P = 0.000). CONCLUSION: Patch testing is a valuable diagnostic aid in lower leg and feet eczema. It plays a pivotal role in identifying causative allergens associated with ACD from which allergen avoidance can be advised for a better clinical outcome and quality of life.
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