口腔癌和肺癌患者的肺结节:隐球菌感染

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
K. Yamagata, Chikako Hirano, N. Kanno, F. Uchida, S. Fukuzawa, T. Yanagawa, H. Bukawa
{"title":"口腔癌和肺癌患者的肺结节:隐球菌感染","authors":"K. Yamagata, Chikako Hirano, N. Kanno, F. Uchida, S. Fukuzawa, T. Yanagawa, H. Bukawa","doi":"10.3390/dj7040102","DOIUrl":null,"url":null,"abstract":"Pulmonary nodules are frequently considered to be a metastatic disease or primary lung tumors in oral cancer patients. We present a case of pulmonary cryptococcosis in a 68-year-old man with oral and lung cancer. This lung cancer was treated with thoracoscopic resection of the right inferior lobe and mediastinal lymph node dissection. Lower gingival cancer was treated with a mandibulectomy, neck dissection, and reconstruction after chemoradiotherapy. A 20 mm cavitary nodule appeared at the left lung S6 one-month after surgery, during post-operative computed tomography. Thoracoscopic partial resection of the left inferior lobe was performed under the suspicion of lung metastasis. Pathology results revealed a pseudo-epithelial granuloma with necrosis and many yeast-shaped fungi with capsules. A pathological diagnosis of Cryptococcus infection was made. The patient was prescribed the antifungal agent fosfluconazole, which was administered intravenously for 1 week and intraoral fluconazole for 12 months. No recurrence of the Cryptococcus infection has been noted after 1.5 years.","PeriodicalId":47284,"journal":{"name":"Open Dentistry Journal","volume":"97 6 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2019-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Pulmonary Nodule in a Patient with Oral and Lung Cancer: Cryptococcus Infection\",\"authors\":\"K. Yamagata, Chikako Hirano, N. Kanno, F. Uchida, S. Fukuzawa, T. Yanagawa, H. Bukawa\",\"doi\":\"10.3390/dj7040102\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pulmonary nodules are frequently considered to be a metastatic disease or primary lung tumors in oral cancer patients. We present a case of pulmonary cryptococcosis in a 68-year-old man with oral and lung cancer. This lung cancer was treated with thoracoscopic resection of the right inferior lobe and mediastinal lymph node dissection. Lower gingival cancer was treated with a mandibulectomy, neck dissection, and reconstruction after chemoradiotherapy. A 20 mm cavitary nodule appeared at the left lung S6 one-month after surgery, during post-operative computed tomography. Thoracoscopic partial resection of the left inferior lobe was performed under the suspicion of lung metastasis. Pathology results revealed a pseudo-epithelial granuloma with necrosis and many yeast-shaped fungi with capsules. A pathological diagnosis of Cryptococcus infection was made. The patient was prescribed the antifungal agent fosfluconazole, which was administered intravenously for 1 week and intraoral fluconazole for 12 months. No recurrence of the Cryptococcus infection has been noted after 1.5 years.\",\"PeriodicalId\":47284,\"journal\":{\"name\":\"Open Dentistry Journal\",\"volume\":\"97 6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2019-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Dentistry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/dj7040102\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Dentistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/dj7040102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 1

摘要

在口腔癌患者中,肺结节常被认为是一种转移性疾病或原发性肺肿瘤。我们报告一例68岁男性伴有口腔癌和肺癌的肺隐球菌病。本例肺癌经胸腔镜右下叶切除及纵隔淋巴结清扫术治疗。下龈癌的治疗是下颌骨切除术,颈部清扫,放化疗后重建。术后计算机断层扫描显示,术后1个月左肺S6处出现20毫米空洞结节。在怀疑肺转移的情况下,行胸腔镜下左下叶部分切除术。病理结果显示假上皮肉芽肿伴坏死及许多酵母状真菌带囊。病理诊断为隐球菌感染。患者给予抗真菌药物氟康唑静脉滴注1周,氟康唑口服12个月。术后1年半未见隐球菌感染复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pulmonary Nodule in a Patient with Oral and Lung Cancer: Cryptococcus Infection
Pulmonary nodules are frequently considered to be a metastatic disease or primary lung tumors in oral cancer patients. We present a case of pulmonary cryptococcosis in a 68-year-old man with oral and lung cancer. This lung cancer was treated with thoracoscopic resection of the right inferior lobe and mediastinal lymph node dissection. Lower gingival cancer was treated with a mandibulectomy, neck dissection, and reconstruction after chemoradiotherapy. A 20 mm cavitary nodule appeared at the left lung S6 one-month after surgery, during post-operative computed tomography. Thoracoscopic partial resection of the left inferior lobe was performed under the suspicion of lung metastasis. Pathology results revealed a pseudo-epithelial granuloma with necrosis and many yeast-shaped fungi with capsules. A pathological diagnosis of Cryptococcus infection was made. The patient was prescribed the antifungal agent fosfluconazole, which was administered intravenously for 1 week and intraoral fluconazole for 12 months. No recurrence of the Cryptococcus infection has been noted after 1.5 years.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Open Dentistry Journal
Open Dentistry Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
2.00
自引率
0.00%
发文量
86
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信