纳米技术在HIV/AIDs检测和治疗中的应用综述

Mope Edwin Malefane
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引用次数: 1

摘要

人们经常抱怨艾滋病毒的研究似乎离“治愈”这个小而有影响力的词越来越近了。毒性、病毒库、社会歧视和耐药性增加了艾滋病毒检测和治疗面临的挑战。纳米技术在药物开发和输送中的应用有望通过产生具有药理优势的药物来对抗和纠正与艾滋病毒治疗相关的问题,这些药物是由纳米尺度上的独特材料特性开创的,与体积、原子尺度或分子尺度相比,纳米尺度上的材料具有独特的药理优势。这篇综述探讨了纳米材料(纳米胶囊、纳米载体、纳米晶体等)在快速检测、治疗和/或预防艾滋病毒方面的不同操作的深刻研究成果。此外,根据已获得的文献调查和意见,提出了未来研究的可能性,作为成功的无艾滋病毒生成和纳米医学的众多进展的路线图。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Applications of Nanotechnology Towards Detection and Treatment of HIV/AIDs: A Review Article
There are frequent grumbles of HIV investigations that appears to be getting whisker close to a minor but influential word cure. Toxicity, viral reservoirs, societal discrimination and drug resistance increases the challenges faced with HIV detection and treatment. Nanotechnological applications in drug development and delivery promises to combat and correct issues associated with HIV treatment through generation of drugs with pharmacological advantages that are pioneered by unique materials properties at nanoscale compared to bulk, atomic scale or molecular dimensions. This mini review explores the profound research findings on different manipulations of nanosized materials (nanocapsules, nanocarriers, nanocrystals, etc.) towards rapid detection and cure and/or prevention of HIV. Moreover, possibilities for future investigations are suggested based on attained literature investigations and opinions as a roadmap towards successful HIV free generation and numerous advances in nanomedicine.
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