急性脑缺血患者大脑半球-小脑-肾的相互作用

O. Kononets, O. Tkachenko, O. O. Kamenetska
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引用次数: 1

摘要

众所周知,神经系统,特别是自主神经系统,能够不断调节身体的内部功能,使其适应不断变化的外部和内部环境参数。特别是,神经系统和肾脏之间存在密切的多向量相关性。本研究的目的是明确急性脑卒中患者神经系统和肾脏并发病变的机制、临床和临床旁特征。本文报告215例缺血性脑卒中患者,年龄70±8.44岁。其中,我们调查了144名女性和71名男性。患者接受全面检查,包括详细的临床和神经系统检查(入院时和发病第21天用美国国立卫生研究院卒中量表(NIHSS)和Barthel指数评估患者病情严重程度)、实验室分析(入院时和发病第21天电解质平衡、氮代谢)和仪器检查(脑部CT扫描、随访脑磁共振成像)。采用统计学方法对数据进行分析。在发病第1天,所有接受调查的右半球颈动脉卒中患者以及绝大多数左半球颈动脉卒中及椎基底系统缺血性卒中患者均出现脑肾综合征,表现为肾浓度滤过功能障碍,伴肾小球滤过率降低。缺血性脑卒中患者肾浓度和滤过功能与右半球缺血灶有可靠的关系,其特点有待明确。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cerebral hemispheres – cerebellum – kidney interaction in patients with acute cerebral ischemia
The nervous system, in particular the autonomic one, is well known to constantly regulate the internal functioning of the body, adapting it to changeable external and internal environmental parameters. In particular, there is a close multiple-vector correlation between the nervous system and the kidneys. The aim of this study was to specify the mechanisms, clinical and paraclinical characteristics of the concomitant lesions of the nervous system and the kidneys in patients with acute stroke. This paper presents the case report of 215 patients, aged 70 ± 8.44, who suffered from ischemic stroke. Among them, we examined 144 women and 71 men. The patients underwent a comprehensive examination, including a detailed clinical and neurological check-up (evaluating the patients’ condition severity with the National Institutes of Health Stroke Scale (NIHSS) and the Barthel index on admission and on the 21st day of the disease), laboratory analysis (electrolyte balance, nitrogen metabolism (on admission and on the 21st day of the disease) and instrumental examination (CT scan of the brain, the follow-up brain magnetic resonance imaging). The statistical methods were used to analyze the data. In the 1st day of the disease, all the surveyed patients with right hemispheric carotid stroke and the overwhelming majority of the patients with left hemispheric carotid stroke and ischemic stroke in the vertebrobasilar system had cerebral renal syndrome, represented by renal concentration-filtration dysfunction, accompanied by the reduced glomerular filtration rate. A reliable relationship was found between the renal concentration and filtration function and the right hemispheric ischemic focus in patients with ischemic stroke, the characteristics are to be specified.
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